Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies.

Objective: The current studies have yielded inconclusive findings regarding the connection between periodontitis  and oral cancer (OC). Therefore, our goal is to elucidate this relationship.

Materials And Methods: We conducted a thorough search of electronic databases (EMBASE, PubMed, Web of Science, and Cochrane Library) up to September 2023.

Comparison study of chewing efficiency in patients with different vertical skeletal patterns of Angle Class I and Angle Class II malocclusions.

Objective: The purpose of this study was to analyze and compare the differences in chewing efficiency among patients with different vertical skeletal types of Angle Class I and Angle Class II malocclusions, to provide reference for orthodontic clinical practice.

Method And Materials: Sample size estimation revealed a minimum of 53 for each class. Thus, a total of 108 patients with Angle Class I and Angle Class II malocclusions were selected.

Identification of rare nonsense variant causing orofacial cleft in a Chinese family and an up-to-date genotype-phenotype analysis.

The Patched 1 () gene encodes a membrane receptor involved in the Hedgehog (Hh) signaling pathway, an abnormal state of which may result in congenital defects or human tumors. In this study, we conducted whole-exome sequencing on a three-generation Chinese family characterized with variable penetrance of orofacial clefts. A rare heterozygous variant in the gene (c.

Three GLI2 mutations combined potentially underlie non-syndromic cleft lip with or without cleft palate in a Chinese pedigree.

Background: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect. Its etiology is complex and it has a lifelong influence on affected individuals. Despite many studies, the pathogenic gene alleles are not completely clear.

A novel PTCH1 mutation underlies nonsyndromic cleft lip and/or palate in a Han Chinese family.

Objectives: Cleft lip and/or palate (CL/P) is the most common craniofacial congenital disease, and it has a complex aetiology. This study aimed to identify the causative gene mutation of a Han Chinese family with CL/P.

Subjects And Methods: Whole exome sequencing was conducted on the proband and her mother, who exhibited the same phenotype.

[Quality evaluation of randomized controlled trials on treatment of cognitive-behavioral therapy on temporomandibular disorders].

Objective: To evaluate methodological and reporting quality of the randomized controlled trials on cognitive-behavioral therapy(CBT) on temporomandibular disorders(TMD).

Methods: The electronic databases of Medline via Ovid, EMBASE, Cochrane Central Register of Controlled Trial, CBM and CNKI, and five Chinese stomatological journals were included to collect randomized controlled trial(RCT) and quasi-RCT(qRCT) on CBT on TMD. Data were assessed using the quality assessment criteria recommended by the Cochrane Collaboration, and the reporting quality was assessed using the consolidated standards of reporting trials (CONSORT) checklist.