Publications by authors named "Maimaiti Abudurufu"
Long non-coding RNA VIM-antisense 1 (VIM-AS1) has been reported that it is involved in the progression of several cancers. However, the aberrant expression profile, clinical significance, and biological function of VIM-AS1in lung adenocarcinoma (LUAD) have not been fully described. We tend to perform a comprehensive analysis to identify the clinical prognostic value of VIM-AS1 for LUAD patients and explore its potential molecular mechanisms in LUAD development.
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- The study investigates methylation of N6 adenosine (m6A)-related long noncoding RNA in the context of 'driver-gene-negative' lung adenocarcinoma (LUAD) to improve patient treatment options.
- Researchers analyzed RNA sequencing data from 46 tumors and normal tissues, identifying 23 m6A regulators and relevant lncRNAs to develop a risk model that effectively stratifies patients into high- and low-risk groups.
- The findings highlight the prognostic value of m6A lncRNAs and suggest that certain lncRNAs like DIO3OS could play a role in cancer development and treatment decisions across different cancer types.