Publications by authors named "Mailys Boutin"
Article Synopsis
- This study investigates the structural features and expression levels of proteins in the human centrosome, revealing that these proteins are generally larger and have more exons than typical human proteins.
- Centrosomal proteins are rich in disordered regions, with 57% of their length being predicted as disordered, contrasting with 39% in general human proteins. Many also exhibit a combination of disordered and coiled-coil regions.
- Expression assays showed that a significant portion of centrosomal proteins (68% of full-length proteins and 74% of domain constructs) were insoluble; structural models were developed for many, but 23% lacked suitable templates due to high disorder predictions.
