Publications by authors named "Maile L Richert"
Background: The purpose of this study was to determine: (1) whether stable heart failure patients with reduced ejection fraction (HFrEF) have elevated extravascular lung water (EVLW) when compared with healthy control subjects; and (2) the effect of acute β-adrenergic receptor (βAR) agonist inhalation on lung fluid balance.
Methods: Twenty-two stable HFrEF patients and 18 age- and gender-matched healthy subjects were studied. Lung diffusing capacity for carbon monoxide (DLCO), alveolar-capillary membrane conductance (Dm), pulmonary capillary blood volume (V) (via re-breathe) and lung tissue volume (V) (via computed tomography) were assessed before and within 30 minutes after administration of nebulized albuterol.
Article Synopsis
- - The study aimed to determine how changes in pulmonary capillary blood volume, lung volume, and interstitial fluid affect lung impedance during different positions and exercise in heart failure patients.
- - Measurements were taken from 12 heart failure patients at rest and during exercise, revealing that lung impedance increased with lung volume and varied when patients changed positions.
- - Results showed that while lung impedance is influenced by volume and position changes, it does not significantly change with small, acute variations in lung fluid during exercise.