Normalization of impaired glucose tolerance after kidney transplantation is associated with improved β-cell function.

Our previous study revealed that over 50% of recipients with pretransplant impaired glucose tolerance (IGT) improved to normal glucose tolerance after kidney transplantation. However, the mechanism is unclear. We aimed to investigate whether the changes in glucose tolerance are associated with β-cell function and insulin resistance in Japanese kidney transplant recipients with pretransplant IGT.

Alanine aminotransferase and γ-glutamyltransferase as markers for elevated insulin resistance-associated metabolic abnormalities in obese Japanese men younger than 30 years of age.

Objective: This study aimed to understand whether liver function tests predict insulin resistance and its associated metabolic abnormalities in obese young men who are younger than 30 years of age.

Methods: In this cross-sectional study, we determined anthropometric and metabolic parameters and the homeostasis model assessment of insulin resistance (Homa-IR) in 208 obese young Japanese men (age, 18-29 years; BMI ± SD, 31.3 ± 3.

Waist circumference is positively associated with insulin resistance but not with fasting blood glucose among moderately to highly obese young Japanese men.

Objective: To investigate the association of waist circumference with insulin resistance in obese young Japanese men.

Methods: In this cross-sectional study, we evaluated 92 obese young Japanese men (age: 18-29 years; mean BMI ± SD: 33 ± 3 kg/m(2)) for anthropometric and metabolic parameters and the homeostasis model assessment of insulin resistance (Homa-IR).

Results: Waist circumference ranged from 87.