Osteopathic treatment in addition to standard care in patients with Gastroesophageal Reflux Disease (GERD) - A pragmatic randomized controlled trial.

Background: Long-term Proton Pump Inhibitor use is associated with low response rates and the risk of adverse events.

Objective: The objective of this study was to assess the effectiveness of Osteopathic Treatment in patients with Gastroesophageal Reflux Disease (GERD).

Methods: This study was a randomized controlled trial with a series of osteopathic interventions and an untreated control group.