Publications by authors named "Maibritt P Klitholm"

Background: Despite improved medical treatment strategies, postoperative pain, nausea, and vomiting remain major challenges. This systematic review investigated the relationship between perioperative respiratory and hemodynamic interventions and postoperative pain, nausea, and vomiting.

Methods: PubMed and Embase were searched on March 8, 2021 for randomized clinical trials investigating the effect of perioperative respiratory or hemodynamic interventions in adults undergoing non-cardiac surgery.

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Background: The optimal ventilation strategy during general anesthesia is unclear. This systematic review investigated the relationship between ventilation targets or strategies (eg, positive end-expiratory pressure [PEEP], tidal volume, and recruitment maneuvers) and postoperative outcomes.

Methods: PubMed and Embase were searched on March 8, 2021, for randomized trials investigating the effect of different respiratory targets or strategies on adults undergoing noncardiac surgery.

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Background: Controversy exists regarding the effects of a high versus a low intraoperative fraction of inspired oxygen (FiO ) in adults undergoing general anesthesia. This systematic review and meta-analysis investigated the effect of a high versus a low FiO on postoperative outcomes.

Methods: PubMed and Embase were searched on March 22, 2022 for randomized clinical trials investigating the effect of different FiO levels in adults undergoing general anesthesia for non-cardiac surgery.

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Background: During general anaesthesia for noncardiac surgery, there remain knowledge gaps regarding the effect of goal-directed haemodynamic therapy on patient-centred outcomes.

Methods: Included clinical trials investigated goal-directed haemodynamic therapy during general anaesthesia in adults undergoing noncardiac surgery and reported at least one patient-centred postoperative outcome. PubMed and Embase were searched for relevant articles on March 8, 2021.

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