Publications by authors named "Maiah Walters"
Article Synopsis
- T3wt is a non-pathogenic reovirus showing potential as a cancer therapy, but genetic modifications were made to enhance its infectivity in cancer cells.
- Super Virus 5 (SV5), a mutant with five oncolytic mutations, demonstrated the largest plaques in breast cancer cells and led to better tumor reduction and survival rates in treated mice compared to T3wt.
- SV5's mechanism of effectiveness hinges on its ability to spread further than T3wt, highlighting the importance of virus spread in enhancing cancer treatment efficacy.