Morbidity and factors associated with frailty in post-COVID-19 elderly patients attended at a reference center.

Objective: To assess the morbidity profile and identify factors associated with frailty syndrome in post-COVID-19 elderly patients treated at the only Reference Center for Elderly Health Care in northern Minas Gerais.

Methods: This is a case series study, utilizing the Clinical-Functional Vulnerability Index-20 (CFVI-20) and Comprehensive Geriatric Assessment (CGA) to characterize and evaluate the health condition of the group. To define the variables associated with frailty, a multivariate analysis was conducted.

Influence of Conservative or Invasive Treatments on the Occurrence of Sequelae in Permanent Successors After Injuries in the Support Tissues of Incisors Deciduous Teeth: A Cohort Study.

Objective: To assess the influence of conservative or invasive treatments on the appearance of sequelae in permanent successor teeth (SPT) after injuries in the support tissues of anterior deciduous teeth (ISTDT).

Methods: This cohort study accompanied 52 children with ISTDT up to the complete eruption of the permanent successor to investigate the presence or not of SPT. Trauma was clinically evaluated according to the International Association for Dental Traumatology.

Death Anxiety Among Users and Non-Users of Psychedelics.

This study is a survey-type, cross-sectional study conducted in Brazil ( = 517), with online data collection taking place from April to June 2022. The main objective of this study was to evaluate the death anxiety in users and non-users of psychedelics. To this end, we also assessed the validity and reliability of the Death Anxiety Scale in Brazil.

Unveiling the potential of pullulan in enhancing ketoprofen release from PHBV filaments.

In this study, sustainable poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and pullulan (PUL)/PHBV filaments were prepared with ketoprofen for scaffold preparation. The research aimed evaluate the influence of pullulan in the filament properties, such as thermal, morphological, and biological behavior. Hansen parameters demonstrated the difference in the miscibility of the polymers and drug in the blend.

Trends in pH-triggered strategies for dental resins aiming to assist in preventing demineralization: A scoping review.

Objectives: To identify and map the literature on the current state of pH-triggered strategies for resin-based materials used in direct restorative dentistry, focusing on innovative compounds, their incorporation and evaluation methods, and the main outcomes.

Data And Sources: Through a search across PubMed, Scopus, Embase, Web of Science, LILACS, Cochrane Library databases, and Google Scholar, this review identified studies pertinent to pH-responsive dental materials, excluding resin-modified glass ionomer cements.

Study Selection: From the 981 records identified, 19 in vitro studies were included, concentrating on resin-based composite resins (50 %), dentin adhesives (25 %), and sealants (25 %).

Comparative finite element analyses of stress exerted on the dentin by intraradicular posts.

Unlabelled: The amount of residual dentin thickness and tooth position in the dental arch is crucial to determine whether an intraradicular post should be used. This study aimed to compare stress distribution on the root dentin of an endodontically treated tooth rehabilitated with CAD/CAM milled glass fiber posts (MP), cast metal posts (CMP), or prefabricated posts (PP) with or without ferrule support, using the finite element method.

Materials And Methods: A human upper central incisor was selected, scanned, and treated endodontically.

Biological Properties of Bioceramic Sealers on Osteoblastic Cells: A Comparative Study.

This study aimed to assess the biological properties of two ready-to-use bioceramic sealers (EndoSequence BC Sealer - EBCS; Bio-C Sealer - BCS) on osteoblastic lineage cells. MC3T3 osteoblast-like cells were exposed to extracts of bioceramic materials. Cytotoxicity was evaluated using the MTT method, genotoxicity was assessed by the micronucleus test and the expression of BMP1, BMP2 and ALP was measured by RT-qPCR, after 1, 3 and 7 days.

Physical-mechanical, chemical and biological properties of graphene-reinforced glass ionomer cements.

Objectives: This study aimed to evaluate the physical-mechanical, chemical, and biological properties of graphene-reinforced glass ionomer cements (GICs).

Materials And Methods: Different proportions of graphene powder were incorporated into 2 high-viscosity self-curing GIC, Ketac Molar (G) and Fuji IX (G), in 4 different concentrations: 0.5%, 1%, 2%, and 5%.

Adherence to Registration and Selective Outcome Reporting in Randomized Clinical Trials Published in Endodontic Journals Over the Past 5 Years: A Meta-Research Study.

Introduction: Prospective registration of randomized clinical trials (RCTs) is highly recommended to ensure research transparency and prevent selective outcome reporting (SOR). This study aimed to evaluate the adherence to registration and the presence of SOR in RCTs published in endodontic journals over the past 5 years.

Methods: Electronic searches were conducted in PubMed and the libraries of the Journal of Endodontics, International Endodontic Journal, European Endodontic Journal, and Australian Endodontic Journal.

Effect of the reduction in the exposure time to at-home bleaching gel on color change and tooth sensitivity: A systematic review and meta-analysis.

Objective: To investigate the effect of reducing exposure time to at-home bleaching gel on color change and tooth sensitivity.

Materials And Methods: The search was carried out using PubMed, Scopus, Web of Science, EMBASE, LILACS, Cochrane. Randomized clinical trials (RCTs) were included involving adult patients who have never undergone bleaching treatment before (P), subjected to bleaching with a reduced exposure time to the at-home bleaching agent (I) compared to those who used it for the time indicated by the manufacturer (C), to evaluate the effects on color change and tooth sensitivity (O).

Quality of life and quality of sleep in health professionals working in critical areas.

Introduction: Emergency rooms and intensive care units in hospitals are physically and mentally stressful for health personnel and can negatively affect them.

Objectives: To evaluate and to compare the quality of life and quality of sleep of emergency room and intensive care unit personnel.

Methods: This is an analytical cross-sectional study conducted with 117 civil servants, including physicians, nurses, and licensed practical nurses.

Salivary Metabolomics in Patients with Long COVID-19 Infection.

Long COVID-19 has been characterized by the presence of symptoms lasting longer than 4 weeks after the acute infection. The pathophysiology of clinical manifestations still lacks knowledge. The objective of this paper was to evaluate metabolite abundance in the saliva of long COVID patients 60 days after hospital discharge.

Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation.

Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the molecular level, actomyosin comprises actin bundles and myosin motor proteins that are sensitive to posttranslational modifications like phosphorylation. While the molecular components of actomyosin are well understood, the coordination of contractility by extracellular and intracellular signals, particularly from cellular signalling pathways, remains incompletely elucidated.

Media Representation of Scientists in Jornal Nacional: Reaffirmation of Stereotypes During the First Year of the COVID-19 Pandemic.

In response to the COVID-19 pandemic, scientific authorities were routinely consulted by mainstream media outlets through interviews, statements and/or supporting images. In this framework, our goal in this study was to analyze the media representation of scientists in Brazil during the first year of this global public health crisis. To this end, we applied a research protocol and, using statistical techniques, quantitatively analyzed newscasts on the country's main TV news program, Jornal Nacional.

COVID-19 Vaccination Acceptance and Hesitancy in Healthcare Workers and the General Population: A Systematic Review and Policy Recommendations.

Introduction: The COVID-19 pandemic challenged the scientific community to find and develop a vaccine to fight the disease. However, problems with achieving high vaccine coverage have emerged, even among high-risk groups such as healthcare workers (HCWs).

Objective: The objective of this study is to examine factors that influence HCW's and the general population's adherence to COVID-19 vaccination and national policies to vaccinate HCWs and other target groups.

Fiscal austerity and municipal health spending: an interrupted time series study.

Objective: To analyze the impact of the fiscal austerity policy (PAF) on health spending in Brazilian municipalities, considering population size and source of funds.

Methods: The interrupted time series method was used to analyze the effect of the PAF on total expenditure, resources transferred by the Federal Government, and own/state per capita resources allocated to health in the municipalities. The time series analyzed covered the period from 2010 to 2019, every six months.

Effect of treatment of transverse maxillary deficiency using rapid palatal expansion on oral health-related quality of life in children: complementary results for a controlled clinical trial.

Objective: To evaluate the effect of rapid palatal expansion (RPE) using Haas-type expanders on children's oral health-related quality of life (OHRQOL) and compare said effect with that previously reported for the use of Hyrax-type expanders.

Materials And Methods: Forty participants aged 8-10 years with transverse maxillary deficiency were treated using Haas appliances. OHRQOL was measured using the CPQ before RPE, during RPE (T), at the end of RPE (T), and 1 month after appliance removal (T).

Impact of Clinical Consequences of Pulp Involvement due to Caries on Oral Health-Related Quality of Life in Children and Adolescents: A Systematic Review and Meta-Analysis.

Introduction: Dental caries with pulp involvement potentially impacts the oral health-related quality of life (OHRQoL). This meta-analysis aimed to evaluate whether clinical consequences of pulp involvement due to dental caries impacts OHRQoL of children and adolescents.

Methods: Observational studies evaluating whether children/adolescents (population) with pulp involvement due to caries (exposition) compared with those without it (comparison) have more negative impact on their OHRQoL (outcome) were included.

Treatment of Ulcerative Lesions with Low-level Laser Therapy in a Patient with SARS-CoV-2.

Ulcerated lesions have been observed in SARS-CoV-2 patients and their treatment is a challenge. We aim to report the treatment of oral lesions with low-level laser therapy (LLLT) in a patient with SARS-CoV-2. The patient diagnosed with COVID-19 was admitted to the intensive care unit, on mechanical ventilation, and on a nasogastric tube diet that persisted due to oral lesions.

Sylvatic Mosquito Viromes in the Cerrado Biome of Minas Gerais, Brazil: Discovery of New Viruses and Implications for Arbovirus Transmission.

Studies on animal virome have mainly concentrated on chordates and medically significant invertebrates, often overlooking sylvatic mosquitoes, constituting a major part of mosquito species diversity. Despite their potential role in arbovirus transmission, the viromes of sylvatic mosquitoes remain largely unexplored. These mosquitoes may also harbor insect-specific viruses (ISVs), affecting arboviral transmission dynamics.

Are educational tools in oral health programs for pregnant women effective in improving the oral status of mothers and babies? A systematic review.

Objective: To analyze, through a systematic review, the effectiveness of educational tools (ETs) in Oral Health Programs (OHPs) for pregnant women in improving their oral status and that of their babies.

Method: Searches were carried out in 5 electronic databases. Randomized (RCTs) and non-randomized clinical trials (CTs) were selected that included pregnant women exposed or not to ETs in OHPs, whose oral health status, in the pre- or postnatal period, or of their babies were verified.

ARE PIT AND FISSURE SEALANTS EFFECTIVE IN PREVENTING AND ARRESTING OCCLUSAL CARIES IN PRIMARY AND PERMANENT TEETH? AN OVERVIEW OF SYSTEMATIC REVIEWS.

Objectives: To compile the evidence from systematic reviews (SRs) about the use of sealants for preventing and arresting pit and fissure occlusal caries in primary and permanent teeth.

Materials And Methods: A search was performed in six databases and gray literature up to May 2023. Systematic reviews (SRs) that included randomized trials (RCTs) and nonrandomized clinical trials (n-RCTs) aiming to answer the PICO-based focused question "are pit and fissure sealants (I) more effective than other interventions, control or no treatment (C) in preventing and arresting occlusal caries (O) in primary and permanent teeth (P)?", were included.