Performance and mechanism of ammonia production by electrocatalytic nitrate reduction based on dodecahydro-closo-dodecaborate hybrid.

Ammonia is an essential food and fertilizer component and is a fundamental raw material for industry and agriculture. In contrast, nitrate is the main pollutant that causes eutrophication in water. Electrocatalysis is a clean and efficient method for simultaneous nitrate removal and ammonia production.

Strong metal-support interactions for high sintering resistance of Ru-based catalysts toward the HER and ORR.

B, N co-doped carbon-supported small-sized Ru nanoparticles (RuBCN) were constructed by a facile ion exchange strategy using -[BH] and Ru(bpy) as the precursors. Benefitting from strong metal-support interactions caused by the synergistic coupling effect of co-dopants B and N, RuBCN exhibits improved sintering resistance and the Ru nanoparticles are stabilized at sub-3 nm at 900 °C. Besides, introducing B doping further increases the electron deficiency of Ru in RuBCN, which could weaken the interaction between Ru and H species or O adsorption.

lncRNA TP73-AS1 Regulates miR-21/PTEN Axis to Affect Cell Proliferation in Acute Myeloid Leukemia.

TP73-AS1 has been reported as an overexpressed oncogenic lncRNA in several types of cancer. However, these analyses of The Cancer Genome Atlas data set revealed downregulation of TP73-AS1 in acute myeloid leukemia (AML). In this study, we aimed to study the molecular mechanism between TP73-AS1 and cell proliferation in AML.

Shape-Controlled Dodecaborate Supramolecular Organic-Framework-Supported Ultrafine Trimetallic PtCoNi for Catalytic Hydrolysis of Ammonia Borane.

On the basis of the unique chaotropic supramolecular assembly of cucurbit[5]uril (CB5) and dodecahydro- closo-dodecaborate anion [ closo-BH], we have developed an efficient and universal platform to fabricate shape-controlled dodecaborate-based supramolecular organic frameworks (BOFs) decorated with ultrafine monodispersed trimetallic alloys. Simply by regulating the molar ratio of CB5 and [ closo-BH], a series of fascinating morphologies, such as flowerlike structures, nanorods, nanocubes, and nanosheets, were successfully constructed. These obtained BOFs were proved to be good substrate supports for in situ synthesis of trimetallic PtCoNi nanoalloys, where the final PtCoNi-BOFs materials were obtained efficiently as a precipitate from aqueous solutions, and showed excellent catalytic performance in ammonia borane hydrolysis with a high turnover frequency of 1490 mol mol min and a low activation energy of 15.

Curculigoside exerts significant anti‑arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF‑κB signaling pathway.

The present study aimed to investigate the anti‑arthritic effects of curculigoside isolated from the rhizome of Curculigo orchioides Gaertn in vivo and in vitro, as well as to determine the potential underlying mechanisms. A rat model of arthritis was induced with type II collagen. Arthritic rats were treated with curculigoside (50 mg/kg) and blood samples were collected to determine serum levels of tumor necrosis factor (TNF)‑α, interleukin (IL)‑1β, IL‑6, IL‑10, IL‑12 and IL‑17A.