Publications by authors named "Mai Yamanaka"
Article Synopsis
- * Out of the 271 eligible patients, the analysis categorized them into four groups based on their malnutrition and cachexia status, revealing that 31% had both conditions, while others had just one or none.
- * Results indicated no significant improvements in activities of daily living or swallowing for those with both conditions compared to those without, but a notable increase in mortality was observed among the groups affected by cachexia.
We investigated the effect of activin A on differentiation of 3T3-L1 preadipocyte. Activin A suppressed the induction of terminal differentiation markers such as glycerol-3-phosphate dehydrogenase (GPDH) activity, lipid accumulation, and the expression of adipocyte fatty acid-binding protein (aP2) mRNA when the cells were treated with activin A throughout the differentiation period. Activin A treatment during the early phase decreased GPDH activity and aP2 mRNA level, and also reduced the expression of peroxisome proliferator-activated receptor (PPAR) gamma and CCAAT/enhancer binding protein (C/EBP) alpha mRNAs without affecting the expressions of the active isoforms of C/EBPbeta and its mRNA.
View Article and Find Full Text PDF