Clinical applications for out-of-office blood pressure monitoring.

Hypertension is one of the most common chronic diseases as well as the leading risk factor for cardiovascular disease (CVD). Efficient screening and accurate blood pressure (BP) monitoring are the basic methods of detection and management. However, with developments in electronic technology, BP measurement and monitoring are no longer limited to the physician's office.

Prognostic and Immunological Role of FUN14 Domain Containing 1 in Pan-Cancer: Friend or Foe?

FUN14 domain containing 1 (FUNDC1) plays a pivotal role in mitochondrial autophagy (mitophagy), which is closely associated with human immunity. However, the role of FUNDC1 in cancers remains unclear. This study aimed to visualize the prognostic landscape of FUNDC1 in pan-cancer and investigate the relationship between FUNDC1 expression and immune infiltration.

IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway.

Background: Bone marrow mesenchymal stem cell (BMSC) transplantation represents a promising therapeutic strategy for ischemic heart disease. However, its effects are hampered by the poor viability of transplanted cells and the hostile microenvironment of the ischemic region. Insulin-like growth factor-1 (IGF-1) is an important paracrine growth factor of BMSC and plays an important role in the properties of BMSC.

Importance of Bi-O Bonds at the CsAgBiBr Double-Perovskite/Substrate Interface for Crystal Quality and Photoelectric Performance.

Interface interactions between perovskite materials and substrates are of great significance for the development of high-quality perovskite materials. Herein, we have successfully prepared CsAgBiBr double-perovskite films via a one-step spin-coating process and demonstrated a novel approach that modifies the surface of substrates with an ultrathin metal oxide (MO) layer to promote the film quality and photoelectric performance. Characterization results strongly suggest that the improvement is attributed to the Bi-O interfacial interaction at substrate/perovskite interface.

The significance of combined detection of CysC, urinary mAlb and β-MG in diagnosis of the early renal injury in pregnancy-induced hypertension syndrome.

Objective: To elaborate the significance of combined detection of cystatin C, urinary micro-albumin (mAlb) and β-microglobulin (β-MG) in diagnosis of the early renal injury in pregnancy-induced hypertension syndrome.

Methods: A total of 120 patients with pregnancy-induced hypertension syndrome who were admitted to this hospital for treatment between November 2015 and October 2018 were enrolled as subjects, and divided into the control group (without complication of renal injury, n = 76) and the observation group (with complication of renal injury, n = 44) according to the complications of early renal injury. Furthermore, 60 patients who participated in the antenatal care in this hospital were enrolled as the normal subjects (normal group).

[Effect of Cu on Denitrification Using NO as an Electron Acceptor].

The short-cut biological nitrogen removal process has been widely used in industrial wastewater treatment, and denitrification is a crucial step for removing nitrogen on which the effect of Cu, a common heavy metal ion in wastewater, has not been studied. In this study, sludge with good short-range biological nitrogen removal characteristics in an A/O reactor was selected to investigate the short-term and long-term effects of Cu on denitrification using NO as an electron acceptor. The results showed that Cu had a significant inhibitory effect on denitrification process using NO as an electron acceptor, and the semi-inhibitory concentration EC of sludge activity was 4.

Circ-DB participates in the progression of gastric cancer by competitively binding microRNA-34a to regulate the expression of MET.

Objective: To figure out the possible role and mechanism of circ-DB in the pathogenesis of gastric cancer (GCa).

Patients And Methods: 32 cases of postoperative GCa tissue samples and adjacent ones were collected and divided into groups of ≥ 5 cm and < 5 cm according to tumor diameter. Circ-DB, microRNA-34a, and MET expressions were detected by real time-quantitative PCR (RT-qPCR) in GCa tissues and adjacent tissues.

mTOR-mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP.

Microglia constantly survey the brain microenvironment and rapidly adopt different phenotypes in response to environmental stimuli. Such dynamic functions require a unique metabolism and bioenergetics. However, little is known about the basic metabolism of microglia and how metabolic changes regulate microglia function.

[Investigation of treatment and analysis of prognostic risk on enterocutaneous fistula in China: a multicenter prospective study].

To investigate the diagnosis and treatment for enterocutaneous fistula (ECF) in China, and to explore the prognostic factors of ECF. A multi-center cross-sectional study was conducted based on the Registration System of Chinese Gastrointestinal Fistula and Intra-Abdominal Infections to collect the clinical data of ECF patients from 54 medical centers in 22 provinces/municipalities from January 1, 2018 to December 31, 2018. The clinical data included patient gender, age, length of hospital stay, intensive care unit (ICU) admission, underlying diseases, primary diseases, direct causes of ECF, location and type of ECF, complications, treatment and outcomes.

Surgical-related risk factors associated with anastomotic leakage after resection for rectal cancer: a meta-analysis.

Objectives: Anastomotic leakage (AL) after anterior resection always leads to longer hospital stays, decreased quality of life and even increased mortality. Despite extensive research, no consensus on the world well-concerned surgical-related risk factors exists. We therefore conducted a meta-analysis of the available published literature to identify the effects of surgical-related risk factors for AL after anterior resection for rectal cancer, hoping to provide more information and improved guidance for clinical workers managing patients with rectal cancer who are at a high risk for AL.

Valence-State Controllable Fabrication of CuO/Si Type-II Heterojunction for High-Performance Photodetectors.

Cuprite, nominally cuprous oxide (CuO) but more correctly CuO, is widely used in optoelectronic applications because of its natural p-type, nontoxicity, and abundant availability. However, the photoresponsivity of CuO/Si photodetectors (PDs) has been limited by the lack of high-quality CuO films. Herein, we report a facile room-temperature solution method to prepare high-quality CuO films with controllable value which were used as hole selective transport layers in crystalline n-type silicon-based heterojunction PDs.

A Robust Solid Electrolyte Interphase Layer Augments the Ion Storage Capacity of Bimetallic-Sulfide-Containing Potassium-Ion Batteries.

Metal-organic framework-derived NiCo S microrods wrapped in reduced graphene oxide (NCS@RGO) were synthesized for potassium-ion storage. Upon coordination with organic potassium salts, NCS@RGO exhibits an ultrahigh initial reversible specific capacity (602 mAh g at 50 mA g ) and ultralong cycle life (a reversible specific capacity of 495 mAh g at 200 mA g after 1 900 cycles over 314 days). Furthermore, the battery demonstrates a high initial Coulombic efficiency of 78 %, outperforming most sulfides reported previously.

Early glottic cancer in a veteran population: Impact of race on management and outcomes.

Objectives: Multiple population studies have shown racial discrepancies in head and neck cancer treatment and outcomes. We sought to characterize the impact of race on clinical outcomes for patients with early glottic squamous cell carcinoma (SCC) in a tertiary institution which provides equivalent access to care.

Methods: We retrospectively reviewed all early glottic (T1-T2) squamous cell carcinoma at a single institution, the Michael E.

Enhancing photoelectrochemical water splitting by combining work function tuning and heterojunction engineering.

We herein demonstrate the unusual effectiveness of two strategies in combination to enhance photoelectrochemical water splitting. First, the work function adjustment via molybdenum (Mo) doping significantly reduces the interfacial energy loss and increases the open-circuit photovoltage of bismuth vanadate (BiVO) photoelectrochemical cells. Second, the creation and optimization of the heterojunction of boron (B) doping carbon nitride (CN) and Mo doping BiVO to enforce directional charge transfer, accomplished by work function adjustment via B doping for CN, substantially boost the charge separation of photo-generated electron-hole pairs at the B-CN and Mo-BiVO interface.

Significantly Enhancing Response Speed of Self-Powered CuZnSn(S,Se) Thin Film Photodetectors by Atomic Layer Deposition of Simultaneous Electron Blocking and Electrode Protective AlO Layers.

Kesterite CuZnSn(S,Se) (CZTSSe) thin film is a promising material for optoelectronic devices. In this work, we fabricate Mo/CZTSSe/CdS/ZnO/ITO (ITO, indium tin oxide) heterojunction photodetectors with favorable self-powered characteristics. The photodetector exhibits exceptional high-frequency photoresponse performance whose -3 dB bandwidth and rise/decay time have reached 1 MHz and 240/340 ns, respectively.

A versatile bottom-up interface self-assembly strategy to hairy nanoparticle-based 2D monolayered composite and functional nanosheets.

Herein, we present a universal bottom-up interface self-assembly of hairy nanoparticle strategy for 2D monolayered composite and functional nanosheets, including polymeric composite nanosheets and functional porous polymer and carbon nanosheets. By using diverse hairy nanoparticles as building blocks, a series of 2D monolayered polymeric composite nanosheets was prepared, demonstrating the universality of our strategy. Furthermore, the 2D polymeric composites could be easily transformed into 2D monolayered functional porous polymer and carbon nanosheets.

Targeting platelet-derived growth factor receptor β inhibits the proliferation and motility of human pterygial fibroblasts.

: Pterygium, a common eye disease with high postoperative recurrence, lacks effective therapeutic strategies. Therefore, it's urgent to identify specific targets to develop rationally targeted molecular drugs for the pterygial therapy. : The cell proliferation and motility were studied in both the primary human pterygial fibroblasts (hPFs) and an pterygium model.

Treatment of real sodium saccharin wastewater using multistage contact oxidation reactor and microbial community analysis.

In this study, multistage contact oxidation reactor (MCOR) with a novel carrier was used for treatment of high-strength sodium saccharin wastewater (SSW) under stepwise increasing salinities from 1.0% to 8.0%.

Atomic-Layer Deposition-Assisted Double-Side Interfacial Engineering for High-Performance Flexible and Stable CsPbBr Perovskite Photodetectors toward Visible Light Communication Applications.

Self-powered photodetectors (PDs) based on inorganic metal halide perovskites are regarded as promising alternatives for the next generation of photodetectors. However, uncontrollable film growth and sluggish charge extraction at interfaces directly limit the sensitivity and response speed of perovskite-based photodetectors. Herein, by assistance of an atomic layer deposition (ALD) technique, CsPbBr perovskite thin films with preferred orientation and enlarged grain size are obtained on predeposited interfacial modification layers.

High-Performance Na-Ion Storage of S-Doped Porous Carbon Derived from Conjugated Microporous Polymers.

Na-ion batteries (NIBs) have attracted considerable attention in recent years owing to the high abundance and low cost of Na. It is well known that S doping can improve the electrochemical performance of carbon materials for NIBs. However, the current methods for S doping in carbons normally involve toxic precursors or rigorous conditions.

The epidemiological trend of acute promyelocytic leukemia over past four decades: a population-based analysis.

The treatment regimens for acute promyelocytic leukemia (APL) dramatically changed over time. However, its survival trend, based on a large sample size has not been reported. Patients diagnosed with APL were accessed from the Surveillance, Epidemiology, and End Results database.

A Retrospective Clinicopathological Study of Osteosarcoma Patients with Metachronous Metastatic Relapse.

: Although osteosarcoma patients receive a standardized treatment, metachronous metastatic relapse still impairs the overall survival (OS). This study aimed to explore the clinicopathological features and prognostic factors of osteosarcoma patients with metachronous metastatic relapse. : We retrospectively analyzed 59 patients, between January 1st, 2004 and December 31st, 2013.

A Flexible Microsupercapacitor with Integral Photocatalytic Fuel Cell for Self-Charging.

With the rapid advancement in different kinds of portable electronics, self-powered systems with small volume and high-performance characteristics have attracted great attention in recent years. It would be rather exciting if one integrated system can not only convert recyclable energy or waste to electricity but also store energy at the same time. Here, flexible all-in-one energy chips composed of urea-based photocatalytic fuel cells (PFCs) and asymmetric microsupercapacitors (AMSCs) are designed on the same plane for powering small portable electronics.