Publications by authors named "Mai Thanh Tan"
Article Synopsis
- - The study analyzed six solvent fractions from ethanolic extracts of flower buds and leaves for their phytochemical contents and antioxidant activities, revealing that the flower bud aqueous fraction (BAF) had the highest phenolic content and antioxidant capacity.
- - The flower bud hexane fraction (BHF) and leaf hexane fraction (LHF) showed notable antibacterial properties, particularly against specific bacterial strains, with DMC from BHF exhibiting even stronger antibacterial activity than the fractions.
- - DMC demonstrated significant inhibitory effects on urease and α-amylase but no effect on α-glucosidase, suggesting potential for developing natural treatments for gastric infections with minimal toxicity to human cells.
Inhibition of Pancreatic Lipase by Flavonoid Derivatives: and Investigations.
Adv Pharmacol Pharm Sci
January 2024
Obesity, characterized by excessive adipose tissue accumulation, has emerged as a crucial determinant for a wide range of chronic medical conditions. The identification of effective interventions for obesity is of utmost importance. Widely researched antiobesity agents focus on pancreatic lipase, a significant therapeutic target.
View Article and Find Full Text PDFAcetylcholinesterase (AChE) and β-secretase (BACE-1) have become attractive therapeutic targets for Alzheimer's disease (AD). Flavones are flavonoid derivatives with various bioactive effects, including AChE and BACE-1 inhibition. In the present work, a series of 14 flavone derivatives was synthesized in relatively high yields (35-85%).
View Article and Find Full Text PDF