Publications by authors named "Mai Quynh Ma"
Proc Natl Acad Sci U S A
March 2022
Article Synopsis
- Skp and SurA are crucial chaperones that assist in the proper folding of outer membrane proteins (OMPs) and prevent misfolding, especially under stress.
- This study utilized single-molecule fluorescence spectroscopy to analyze how Skp and SurA bind to the unfolded OmpX protein and their roles in disaggregation activities.
- Results showed that both chaperones uniquely expand and rearrange the structure of unfolded OmpX, and they work synergistically to effectively disassemble OmpX aggregates, showcasing their intricate functionalities and energetic interactions during OMP biogenesis.
