Publications by authors named "Mai Kodama"

A 80-year-old man was transferred to our hospital for hemoptysis caused by erosion(perforation) of thoracic aortic stent graft infection into the airway. Blood cultures on admission detected Gram-positive rods, and a microarray-based, multiplexed, automated molecular diagnosis instrument (Verigene® system) identified spp. Although is rare organism of stent graft infection, we were able to start appropriate antibiotic therapy on the second hospital day due to rapid identification of bacteria.

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The 2-step method is an algorithm to detect toxigenic . We herein compared the sensitivities and specificities of an enzyme immunoassay (toxin A/B-EIA), toxigenic culture (TC-EIA), Loop-Mediated Isothermal Amplification assay (LAMP), and Xpert (Xpert) with the detection of the toxin B gene by a polymerase chain reaction (PCR). The results obtained showed that the sensitivities and specificities of toxin A/B-EIA, Xpert, TC-EIA, and LAMP were 30 and 100%, 87.

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A 79-year-old man with a history of tuberculosis was found to have chronic empyema in the right lung and was diagnosed with malignant diffuse large-cell lymphoma (Ann Arbor stage IIE). After completion of one course of rituximab plus cyclophosphamide, pirarubicin, vincristine, and prednisolone (R-CHOP) chemotherapy, the patient developed lung abscess and sepsis caused by Streptococcus intermedius. This condition was treated with antimicrobial agents, and chemotherapy was resumed.

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Microsemi LC-767CRP (LC-767, Horiba, Ltd.) is capable of simultaneous measuring of complete blood count (CBC) including 3-part differentials (3-part Diff.) of white blood cells (WBC) and C-reactive protein (CRP) in 4 minutes.

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Article Synopsis
  • Respiratory quinolones (RQs) are effective against various bacterial infections but are facing rising resistance issues.
  • The study evaluated the effectiveness of four RQs against nine different bacterial species using Monte Carlo simulations, focusing on factors like patients' renal function.
  • Results indicated that Gram-positive cocci showed significant resistance to levofloxacin, while Gram-negative E. coli displayed decreased susceptibility; renal function influenced the efficacy of RQs, particularly for levofloxacin against several bacteria.
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A 65-year-old woman developed fever and dyspnea and visited the emergency department of our hospital. On arrival she was hypoxic, and chest CT showed bilateral centrilobular nodules, infiltrative shadows and bronchial wall thickening. Gram staining wasn't performed on admission, and the urinary antigen-detection test for Streptococcus pneumoniae couldn't be performed because the patient has suffered from anuria caused by renal failure.

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