Publications by authors named "Mai Kabayama"

Previous studies suggest older patients with multiple health conditions and medications may experience adverse interactions, leading to negative outcomes. However, there's limited research on this in older adults receiving home medical care. This study assesses whether polypharmacy is linked to falls or other clinical outcomes.

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  • - The study investigated the link between high-sensitivity C-reactive protein (hs-CRP) levels and cognitive decline in Japanese individuals aged 70 and 80, as previous research provided inconclusive results on this association.
  • - Data from 872 participants were analyzed, revealing that approximately 70% of 70-year-olds and over 80% of 80-year-olds showed low cognitive function, with significant associations found between higher hs-CRP levels and cognitive impairment in both age groups.
  • - The findings suggest that elevated hs-CRP levels may negatively impact cognitive function, highlighting the need for further exploration in the context of inflammation and cognitive health among older adults.
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Aim: This study aimed to examine the influence of the COVID-19 pandemic on physical components and activity, and its relationship to physical performance in older adults.

Methods: Sixty-seven participants aged 75 and older (81 ± 2 years, female: 66%), who underwent medical checkups continuously from 2018 to 2022 in one clinic, were enrolled. Muscle mass was assessed by the biometrical impedance analysis method, which was adjusted by height squared.

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  • - The study investigates the link between respiratory function and mild cognitive impairment (MCI) in older adults living in the community, as aging is known to affect cognitive abilities.
  • - Researchers analyzed respiratory function using spirometry on 419 participants around 73 years old and 348 participants around 83 years old, finding that poorer respiratory metrics correlated with declining cognitive performance, particularly in those aged 83 and older.
  • - The findings suggest that advanced airflow limitations may worsen cognitive dysfunction and that specific respiratory measures, like low peak expiratory flow and vital capacity, could indicate a higher risk of MCI, especially in older women.
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Aim: Vitamin D (VD) affects skeletal muscles. The high prevalence of VD deficiency in Japan may lead to decreased skeletal muscle mass and strength, increasing the prevalence of sarcopenia. Therefore, we aimed to investigate the association between serum VD levels and skeletal muscle indices in a Japanese community-dwelling older population.

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Aim: This study aims to identify the key risk factors that lead to subtypes of physical frailty assessed by walking speed and grip strength among community-dwelling Japanese individuals, stratified by the presence of musculoskeletal diseases (MSDs) and age group.

Methods: We included 302 participants aged 70 or 80 years who did not exhibit subtypes of physical frailty at baseline through the Septuagenarians, Octogenarians, Nonagenarians, Investigation with Centenarians (SONIC) study. Our study was a longitudinal study.

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Patient/family complaints are a valuable source of information for providing patient-oriented healthcare. This study aimed to identify and systematize patient/family complaints about healthcare services, focusing on complaints caused by "things." A qualitative descriptive study was designed.

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Background: We prospectively examined the effect of baseline multimorbidity and polypharmacy on the physical function of community-dwelling older adults over a three-year period.

Methods: The analysis included 1,401 older adults (51.5 % women) who participated in both wave 1 and wave 2 (3-year follow-up) of the Septuagenarians, Octogenarians, and Nonagenarians Investigation with Centenarians (SONIC) study.

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Aim: The serum creatinine/cystatin C ratio (CCR) or sarcopenia index is considered a useful marker of muscle mass. However, its usefulness in late-stage older adults remains unclear. We aimed to determine the usefulness of CCR as an indicator of sarcopenia in community-dwelling Japanese adults aged >75 years.

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Objectives: This study aimed to investigate the association between the number of teeth, food intake, and cognitive function in Japanese community-dwelling older adults.

Methods: This 9-year longitudinal study included a total of 293 analyzable participants who participated in baseline and follow-up surveys. Dental status (number of teeth and periodontal pocket depth), dietary assessment using the brief-type self-administered diet history questionnaire, cognitive function, and the following confounding factors were evaluated: educational level, financial satisfaction, living situation, smoking and drinking habits, history of chronic diseases, apolipoprotein E-ε4 carrier, body mass index, handgrip strength, instrumental activities of daily living, and depressive symptomatology.

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Aim: To examine the actual conditions of older patients receiving home medical care after hospitalization over a period of 2 years in Japan.

Methods: The study population included 102 participants, aged ≥65 years, receiving home medical care, who consented to participate in the Osaka Home Care Registry (OHCARE) study in Japan over a period of 2 years. We investigated the actual conditions for returning home after hospitalization.

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  • The study aimed to identify factors influencing chewing difficulties in Japanese adults aged 70 and 80, as these difficulties may limit food diversity in older populations.
  • Researchers surveyed 1,680 participants, categorizing them into those who experience chewing difficulties and those who do not, based on their ability to eat various foods.
  • Key findings revealed that age, number of remaining teeth, occlusal force, and depression were significant factors associated with subjective chewing difficulties for different types of food.
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Background: The present study investigated lifestyle risk factors from metabolic syndrome-related lifestyles for a rapid decline in the estimated glomerular filtration rate (eGFR) among adults aged 40-74 years with treated and untreated type 2 diabetes.

Methods And Results: This study analyzed data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan, encompassing the period from fiscal year (FY) 2017 to FY2020. We established FY2018 as our baseline year.

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Objective: This study aimed to identify the factors influencing home blood pressure measurement (HBPM) continuation in community-dwelling older adults.

Methods: A longitudinal analysis used the NOSE study intervention group datasets. The participants were encouraged HBPM with self-monitoring devices provided to them twice in the morning and twice in the evening.

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  • The study investigates the relationship between changes in occlusal support (the contact of upper and lower teeth) and masticatory performance (ability to chew) over a 6-year period in older adults.
  • Researchers followed 488 participants aged 72-74, categorizing them based on their occlusal support status (complete, reduced, or collapsed) and found significant factors affecting chewing ability.
  • Results indicate that declining occlusal support is a key contributor to decreased chewing performance, emphasizing the importance of maintaining posterior occlusal support in older adults to enhance their ability to chew effectively.
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  • * Researchers assessed frailty using the Japanese version of Cardiovascular Health Study criteria and sleep status using the Pittsburgh Sleep Quality Index (PSQI), highlighting differences in sleep duration and quality amongst age groups.
  • * The findings indicated that in participants in their 70s, long sleep duration and sleep medication use correlated with frailty, while in those in their 80s, poor sleep quality was linked to frailty, suggesting tailored approaches to sleep evaluation can aid in preventing frailty.
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Purpose: Individuals with impaired masticatory function tend to prefer soft foods, which results in decreased masticatory muscle activity. This study examined the association between the oral condition (number of teeth, occlusal force, and occlusal contact area) and dietary hardness using a daily dietary questionnaire.

Methods: This cross-sectional study evaluated 1841 participants aged 69-71 and 79-81 years.

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While previous studies suggest that women have higher anxiety than men regarding COVID-19, underlying mechanisms remain unclear. This study tries to explain the mechanisms by gender difference in social interaction based on a theory of social amplification of risk framework (SARF). We surveyed older adults in Japan regarding their anxiety regarding COVID-19, as well as the frequencies of their direct and indirect social interaction in July 2020 ( = 1,587, aged 78-99 years).

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Aim: The purpose of this study was to examine the relationship between glycemic control and mental health in community-dwelling older people with diabetes mellitus (DM) from insights that contribute to the management of diabetes in consideration of quality of life (QOL).

Methods: We used the data of the Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) study, a prospective cohort study of community-dwelling older people. The present study included 2,051 older subjects of 70±1 years, 80±1 years and 90±1 years of age.

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  • This study investigates the validity of a health assessment questionnaire with 12 items to measure frailty in older adults.
  • It analyzed data from 461 Japanese individuals aged 78-81, using methods like ROC curve analysis and logistic regression to assess the association between the questionnaire scores and frailty.
  • The findings suggest that scoring 3 or 4 points on the questionnaire is indicative of frailty, with a notable correlation identified between higher scores and increased odds of being frail.
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The associations among cognitive function, hypertension, and dyslipidemia in older adults are controversial. Therefore, we investigated the associations among cognitive decline, hypertension, dyslipidemia, and their combination in community-dwelling older people in their 70s, 80s, and 90s in the long-term observational Septuagenarians, Octogenarians, Nonagenarians, Investigation with Centenarians (SONIC) study. We administered the Montreal Cognitive Assessment Japanese version (MoCA-J) by trained geriatricians and psychologists, and conducted blood testing and blood pressure (BP) measuring by medical staff involving 1186 participants.

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