Publications by authors named "Mai Kaaki"
Article Synopsis
- Klebsiella pneumoniae is a significant healthcare threat due to the rise of hypervirulent and multidrug-resistant strains, which poses challenges in treatment options.
- A genomic analysis of 328 MDR K. pneumoniae strains from a hospital in Jeddah, Saudi Arabia, revealed the dominance of Clonal Complex 14, particularly the ST2096 strain, which has shown continuous expansion.
- The study highlights the strains' ability to acquire resistance genes and their high virulence, with significant clinical implications that underscore the need for monitoring and understanding these emerging strains to prevent outbreaks.
Purpose: The aim of the study is to estimate the prevalence rate of carbapenem-resistant Enterobacteriaceae (CRE) and to determine the types of carbapenemase genes present in patients admitted to King Abdulaziz Medical City (KAMC-J) and King Abdulaziz University Hospital (KAUH), both in Jeddah, Saudi Arabia.
Methods: A total of 180 isolates were analyzed which were included on the basis of retrospective chart review of patients from KAMC-J and KAUH between 1 April 2017 to 30 March 2019. The prevalence of carbapenemase genes was evaluated by Xpert® Carba-R (Cepheid, Sunnyvale, CA, USA).
Background: Nosocomial infections caused by multi-drug resistant are a global public health threat that ought to be promptly identified, reported, and addressed accurately. Many carbapenem-resistant -associated genes have been identified in Saudi Arabia but not the endemic carbapenemases (KPCs), which are encoded by genes. KPCs are known for their exceptional spreading potential.
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