Immune responses on allograft heart transplantation in inbred rats infected with Echinococcosis multilocularis.

Background: Alveolar echinococcosis (AE) is caused by the metacestode stage of Echinococcus multilocularis (E. multilocularis) and is a rare but life-threatening disease. This disease commonly is characterized by an infiltrative, tumor-like growth of the E.

[Effect of different drugs on Echinococcus multilocularis metacestodes in vitro ].

Objective: To test the effect of 6 drugs or combination on the in vitro cultured Echinococcus multilocularis (Em) metacestodes.

Methods: The drugs used included albendazole (ABZ), itraconazole (ITZ), ivermectin, miltefosine, nitazoxanide (NTZ), and rifampin. The Em metacestodes were cultured for 5 weeks and divided into 17 groups each with 120-140 cysts: ABZ groups (1 microg/ml and 10 microg/ml), ITZ group (0.