Fabrication, spectroscopic and photofunctional studies of layered lutetium-dysprosium hydroxides.

The spectroscopic studies of layered rare-earth hydroxides (LRHs) have aroused great interests owing to the unique features of combing rare-earth ions with diverse anions. In this work, some anions were incorporated into layered lutetium-dysprosium hydroxides (LLuH:Dy) by the hydrothermal and ion exchange process, in which Dy ion acted as the emission center. The results manifest that the assemblies possess clearly lamellar structure and flake shape, and emit the characteristic yellow and blue light of Dy under ultraviolet excitation.

Triptolide inhibits epithelial ovarian tumor growth by blocking the hedgehog/Gli pathway.

Epithelial ovarian cancer (EOC), the most predominant subtype of ovarian cancer (OC), involves poor prognosis and exhibits high aggression. Triptolide (TPL), like other Chinese herbs, has historically played a significant role in modern medicine. The screening system based on Gli-dependent luciferase reporter activity assessed the effects of over 800 natural medicinal materials on hedgehog (Hh) signaling pathway activity and discovered that TPL had an excellent inhibitory effect on Hh signaling pathway activity.