[Effect of drugs on endoscopic manometry of the sphincter of Oddi].

We used a catheter passing through the papilla duodeni under the view of endoscope, with persistent perfusion system and transducer, to measure the pressure and contraction frequency of sphincter of Oddi (SO) in 10 healthy persons and 20 patients. Meanwhile, we compared the effect of Buscopan, Nitrostat and Vitamin K3 on the pressure and contraction frequency (CF). SO basal pressure (BP) in healthy group was 5.

Effect of glass ceramic and titanium implants on primary calcification during rat tibial bone healing.

The effect of bone bonding (KG Cera, Mina 13, and titanium) and nonbone bonding (KGy-213, M 8/1) implants on primary calcification in endosteal bone was examined by comparing changes in the morphometry of matrix vesicles to those occurring during normal bone healing following ablation of rat tibial marrow. The concentration of matrix vesicles, their diameter, and their distance from the calcification front were determined using computerized cytomorphometry at the transmission electron microscopic level. The results demonstrated that bone bonding materials supported an increase in matrix vesicle concentration when compared with control bone at 6 and 14 days postimplantation.

[Clinical significance of peripheral blood T-lymphocyte subsets to herpes simplex keratitis].

The peripheral blood T-lymphocyte subsets in 52 patients with herpes simplex keratitis (HSK) were assessed with monoclonal antibodies. There was marked decrease in WuT3+ and WuT4+, and increase in WuT8+ with consequent diminution of WuT4+/WuT8+ ratio in stromal HSK, while in superficial HSK the above cell counts differed insignificantly from those of the normal controls. These findings suggested that there was immunoregulatory aberration in cases of stromal HSK.

[Value of CEA determination in follow-up of patients with liver metastasis of colorectal cancers with loco-regional chemotherapy].

The importance of carcinoembryonic antigen as a tumor marker to the follow-up of patients with liver metastases from colorectal cancer was investigated. It was reported about 29 patients receiving chemotherapy. We estimated the effect of therapy according to sonographic and computer tomographic criteria and related to the CEA-level.

[Omeprazole in peptic ulceration: acid inhibition and endoscopic healing].

Basal and pentagastrin stimulated gastric acid secretions were measured in 20 patients with duodenal ulcer before and after one week of treatment with oral omeprazole 20 mg daily. Omeprazole markedly inhibited gastric acid secretion in all the patients. The mean basal intragastric pH rose from 1.

The diagnostic significance of carbohydrate antigen CA 19-9 in serum and pancreatic juice in pancreatic carcinoma.

CA 19-9 is a carbohydrate antigen isolated from human colon carcinoma cell line, and is reportedly a tumor marker for pancreatic carcinoma. In this study we determined serum CA 19-9 in 71 normal subjects, 103 patients with benign digestive diseases, 85 patients with periampullary cancers, and 160 patients with other digestive cancers. Serum CA 19-9 was elevated only in 2.

Quantitative evaluation of left ventricular function using computed tomography.

Computed tomography (CT) provides a noninvasive technique with high resolution cross-sectional tomographic images which allow volume measurements of an object, independent of its geometric configuration. A phantom of known volume with controllable periodic motion was used to validate the CT method of volume determination. A good correlation (P less than 0.

Increased carbon dioxide production in two patients with malignant hyperpyrexia and its control by dantolene.

Two patients with successfully treated malignant hyperpyrexia are reported. Carbon dioxide output, calculated from the respiratory minute volume and PaCO2, was found to be greatly increased in both patients. In the patient who received dantolene 7.