Background: The introduction of the varicella vaccine has led to a significant decrease in pediatric varicella-induced invasive (group A streptococcal [GAS]) infections. However, the development of a pleural empyema following a chickenpox infection is a rare complication in pediatric patients.
Case Presentation: In this report, we present a 5-year-old male patient who presented to the emergency department with a deteriorating course two days after a chickenpox infection.