Interferon-Induced Transmembrane Protein-3 Rs12252-G Variant Increases COVID-19 Mortality Potential in Egyptian Population.

Coronavirus disease 2019 (COVID-19) represented an international health risk. Variants of the interferon-induced transmembrane protein-3 () gene can increase the risk of developing severe viral infections. This cross-sectional study investigated the association between rs12252A>G single nucleotide polymorphism (SNP) and COVID-19 severity and mortality in 100 Egyptian patients.

Impact of serum IL 10 on prediction of early allograft rejection in liver transplantation.

Tissue transplantation is the preferred treatment for end organ failure such as heart, lung, kidney, and liver. The immune system recognizes the transplant as non self if the donor and recipient are not genetically identical. Multiple cytokines are involved in this process; however, little is known about their predictive role in rejection.

Appropriateness of hospital admissions in a university hospital in Egypt: Analyzing a preintervention phase.

Background: Identifying the magnitude of this improper use and applying interventions to eliminate unnecessary hospitalization will reduce health-care expenditure, improve the quality of care for patients, and increase the accessibility to care for actual patients in need on waiting lists. Aim of Work To measures the rate of inappropriate admissions at the Ain Shams University Hospital.

Methods: This research is the preintervention phase of a study conducted to improve the appropriateness of patient admission at this hospital.

Natural killer NKG2A and NKG2D in patients with colorectal cancer.

Background: Natural-killer group 2 (NKG2), a characteristic receptor of natural killer (NK) cell family, assumes a vital role in modulating NK cytotoxic function. We aimed to detect mRNA expression of both NKG2A and NKG2D in serum NK cells obtained from colorectal cancer (CRC) patients.

Methods: We enrolled 36 patients with newly diagnosed CRC, as well as 15 group matched healthy individuals.

Assessment of hepatic fibrosis and necroinflammation among inactive HBsAg carriers in Egypt.

Unlabelled: INTRODUCTION. The inactive hepatitis B surface antigen (HBsAg) carrier state is usually characterized by minimal or absent liver pathology. However, in developing countries, owing to the very early age of infection with hepatitis B virus (HBV), this state is reached after a very prolonged immune tolerant and immune reactive phase, during which considerable liver damage may have occurred.