Design of a DOPC-MoS/AuNP hybrid as an organic bed with higher amplification for miR detection in electrochemical biosensors.

The liposome-based biosensors are used for detection of nucleic acids and proteins as organic beds which are biocompatible tools for point of care tests, but their lack of sensitivity has been challenging. Therefore, designing a proper strategy is vital to increase the sensitivity of the target in diagnostic tests. In this study, for the first time, we use a combination of cationic DOPC liposome (dioleoylphosphatidylcholine) with MoS to enhance the sensitivity of liposomal sensors clearly.