Publications by authors named "Mahvish Hussain"

Article Synopsis
  • This study aims to examine the histopathology and outcomes in patients with retinoblastoma who underwent eye enucleation and had neovascular glaucoma (NVG).
  • The research included 1,420 total cases from five continents, revealing that 16% of patients with NVG were often at higher risk of severe histopathological findings.
  • The findings indicate that NVG is linked to more aggressive forms of the disease and a higher chance of metastasis, emphasizing the need for careful monitoring and treatment in these cases.
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Purpose: To compare the clinical outcomes of children with unilateral retinoblastoma (Rb) and high-risk histopathology features (HRHF) following upfront enucleation with/without adjuvant chemotherapy, and investigate cases locally considered non-HRHF but converted to a standardized HRHF definition.

Design: Retrospective multinational clinical cohort study.

Methods: Children with Rb who presented to 21 centers from 12 countries between 2011-2020, and underwent primary enucleation were recruited.

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Article Synopsis
  • The study aimed to analyze high-risk histopathological features in eyes with retinoblastoma (RB) after enucleation and compare patient outcomes globally.
  • A total of 1,426 RB cases were reviewed, revealing significant differences in histopathological features across continents, with Asia showing the highest rates of massive choroidal invasion and optic nerve invasion.
  • The findings indicated that patients from South America and Asia faced greater risks of tumor recurrence, systemic metastasis, and mortality compared to those from Australia, Europe, and North America.
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Background: Salivary gland tumours constitute heterogeneous group of tumours with different biological behaviour and account for 3% of all head and neck tumours. This study was conducted to study the clinico-pathological spectrum of salivary gland tumours.

Methods: The study is a review of 91 cases of salivary gland tumours reported at Chugtai's Lahore Laboratory from 2009-2011.

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Objectives: In this report, we share our experience about the common types of childhood hepatic tumours during 10 years (2001-2010) and compare them with other studies.

Methods: During 10 years (2001-2010), all the hepatic tumours of childhood received at Pathology Department of the Children Hospital and Institute of Child Health, Lahore Pakistan are recorded. This includes both resected specimens and biopsies.

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Background: Ovaries are common site of non-neoplastic and neoplastic lesions. They can present from the neonatal period to post menopause. Most are functional in nature and resolve with minimal treatment.

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