Overuse of the antipyretic agent Paracetamol (PCM) is linked to hepatotoxicity, which limits its clinical use. The goal of this investigation was to find out how well Balsamodendron mukul (B. mukul) extract protects the liver from acute PCM poisoning.
View Article and Find Full Text PDFObjective: The main objective of the study was to evaluate the cytotoxicity of selected essential oils on human skin, gastric, and brain cancer cell lines using microculture tetrazolium test.
Materials And Methods: Phytochemical analysis, as well as acute oral toxicity tests, was carried out in female albino mice with cardamom oil, lemon oil, and jasmine oil according to the Organization for Economic Co-operation and Development guidelines 425. Anticancer activities of the above test drugs were performed using human cancer cell lines.
Objective: To isolate the phytoconstituents from the methanolic extracts of the stem bark of and , characterize spectroscopically and screen for immunomodulatory activity on human neurophils.
Methods: A flavonoid (PGF) and an alkaloidal compound (PGA) from the extract of and a steroidal compound (FGS) and tannin fraction (FGT) from the extract of were isolated using column chromatography technique and were subjected for the spectroscopic (FT-IR, HNMR and LC-MS) and TLC studies to identify the compounds. The isolated compounds were screened for immunomodulatory activity on human neutrophils using nitroblue tetrazolium (NBT) dye test, phagocytosis of and neutrophil locomotion and chemotaxis assay at the concentration range of 100, 50, 25, 12.
Objective: The objective of the present study was to evaluate the antifertility activity of ether (ErCD), chloroform (CeCD) and ethyl alcohol (EyCD) extracts of the whole plant of in female Wistar albino rats.
Methods: Acute oral toxicity and an antifertility study were performed in female Wistar rats with two dose levels (200 and 400 mg/kg, orally) of EyCD. The estrogenic and progestogenic effects of EyCD were further observed by administering it to immature Wistar rats by investigations of vaginal cornification, hormonal level, uterus weight, biochemical parameters, histopathology of the uterus and deciduoma formation, respectively.
Objective: To evaluate the immunomodulatory activity of methanolic extracts of fruit and bark of Ficus glomerata Roxb. on cyclophosphamide-induced myelosuppression in mice and the phagocytic effect on human neutrophils.
Materials And Methods: Methanolic extracts of fruits and bark of Ficus glomerata Roxb.