Publications by authors named "Mahtash Malekian"

Article Synopsis
  • A study looked at how to find out why some babies are born with problems, known as congenital anomalies (CAs), especially in families where cousins marry.
  • They tested different methods on 168 kids with CAs, finding that a method called exome sequencing (ES) worked better than another method called chromosomal microarray analysis (CMA) for families where cousins marry.
  • The results suggest that using ES first can help doctors discover these problems more effectively in those families.
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TGF-β signaling pathways promote tumour development and control several downstream genes such as CTGF and MMPs. This study aimed to investigate the association between CTGF and MMP-1 mRNA expressions with clinicopathological status and survival rate in colorectal cancer patients. We investigated expression levels of CTGF and MMP-1 genes in paraffin-embedded tumours and adjacent normal tissue blocks (ADJ) by Real Time-PCR.

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