Publications by authors named "Mahtab Khoshkholgh Sima"
Article Synopsis
- Antibiotic resistance in Enterobacteriaceae poses significant global health concerns, particularly through mechanisms like overexpression of efflux pumps, which can lead to multidrug resistance (MDR) in bacterial infections.
- A study evaluated the prevalence of specific genes associated with efflux pumps in 100 clinical isolates collected from various infected patients, revealing that 37% of the isolates carried at least one resistance gene, while 12% had both.
- Results showed that all isolates were susceptible to imipenem, but exhibited high resistance rates to other antibiotics like piperacillin and ceftriaxone, highlighting the need for antibiotic monitoring to control the rise in MDR strains in Iran.
Background: Legionnaires' disease is an important public health problem that can cause substantial mortality and morbidity. Legionnaires' disease-risk estimation may be compromised by uncertainties in -detection methods. The aim of this study was the detection of in respiratory specimens of hospitalized patients with respiratory symptoms by culture, PCR, and loop-mediated isothermal amplification (LAMP) methods.
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