Associations between an MDM2 gene polymorphism and ulcerative colitis by ARMS-PCR.

Ulcerative colitis is a form of inflammatory bowel disease characterized by chronic inflammation of the colon and rectum. The abnormal lesions in the digestive system caused by ulcerative colitis and intermittent colitis are of major clinical importance. MDM2 is a phospho-protein that functions as a ubiquitin ligase for p53.

rs1016860 of BCL2 3'UTR associates with hsa-miR-629-5p binding potential in breast cancer and gastric cancer in Isfahan population.

Introduction: Breast cancer is caused by the interaction of inherited and environmental risk factors. Also, gastric cancer is the second fatal carcinoma. B-cell leukemia/lymphoma 2 gene family plays a crucial role in carcinogenesis by inhibiting the apoptosis process.