Publications by authors named "Mahsa Ghaffari Novin"
Article Synopsis
- The study aimed to assess the effects of curcumin nanoemulsion (CUR-NE) on spermatogenesis in mice with testicular damage caused by cyclophosphamide (CP).
- 28 adult male mice were divided into four groups to evaluate various sperm metrics, hormone levels, and testicular health after treatment with CUR-NE and CP.
- Results showed that CUR-NE improved sperm quality and hormone levels while reducing oxidative stress, suggesting it may help promote spermatogenesis in cases of CP-induced testicular toxicity.
Background: Obesity is regarded a global public health crisis. It has been implicated in a variety of health problems, but when it comes to male fertility, how and to what extent obesity affects it are poorly understood. Accordingly, semen samples from 32 individuals with obesity (body mass index (BMI) ≥ 30 kg/m) and 32 individuals with normal weight (BMI: 18.
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- Chemotherapeutic drugs like busulfan harm sperm production, prompting this study to examine how edaravone affects sperm regeneration in mice treated with busulfan.
- The research divided 40 male mice into four groups to analyze various sperm parameters and hormone levels after treatment with edaravone and busulfan.
- Results indicated that edaravone significantly enhanced sperm quality and hormonal levels while reducing cellular damage, highlighting its potential as a protective agent against chemotherapy-induced infertility.
The primary objective of this study is to evaluate and to compare the effects of photobiomodulation (PBM) on sperm parameters both before and after cryopreservation. In this regard, 24 freshly ejaculated semen samples from normozoospermic men were included in this study. Each semen sample was randomly divided into three groups (1 ml aliquot for each group): the control group (group one) underwent conventional sperm cryopreservation (n = 24), group two underwent pre-freezing PBM exposure (810 nm, diode laser, and 0.
View Article and Find Full Text PDFExercise is considered to be a "medicine" due to its modulatory roles in metabolic disorders, such as diabetes and obesity. The intensity and duration of exercise determine the mechanism of energy production by various tissues of the body, especially by muscles, in which the requirement for adenosine triphosphate (ATP) increases by as much as 100-fold. Naturally, athletes try to improve their exercise performance by dietary supplementation with, e.
View Article and Find Full Text PDFmiRNAs are evolutionarily conserved non-coding ribonucleic acids with a length of between 19 and 25 nucleotides. Because of their ability to regulate gene expression, miRNAs have an important function in the controlling of various biological processes, such as cell cycle, differentiation, proliferation, and apoptosis. Owing to the long-standing regulative potential of miRNAs in tumor-suppressive pathways, scholars have recently paid closer attention to the expression profile of miRNAs in various types of cancer.
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