Optimal injected dose ratio of a very rapid 1-day protocol of myocardial perfusion imaging with cadmium-zinc-telluride single-photon emission tomography: simulation and phantom study.

Objective: Cadmium-zinc-telluride detectors enable shorter acquisition durations in myocardial perfusion imaging (MPI), but the time interval of sequential scanning is still unchanged in clinical practice. We designed a very rapid 1-day protocol of MPI using cadmium-zinc-telluride single-photon emission tomography and evaluated the optimal dose ratio between two scanning acquisitions by means of simulations and phantom experiments.

Methods: We intended to perform a 1-day MPI within 140 min and simulate radioactivities in the second scan under various injected dose ratios.