Publications by authors named "Maho Kakemizu-Watanabe"
Article Synopsis
- Preoperative left ventricular (LV) measurements like ejection fraction (LVEF) and end-systolic dimension (LVESD) are key indicators of potential heart dysfunction after mitral valve repair for mitral regurgitation.
- Researchers studied 622 patients, analyzing various echocardiography (TTE) parameters to identify predictors of early postoperative LV dysfunction and significant declines in LVEF.
- Findings revealed that E-wave velocity, along with LVESD and LVEF, emerged as a strong predictor for postoperative LV dysfunction, with specific E-wave velocity thresholds indicating higher risks.
Cerebral tissue oximetry with near-infrared spectroscopy (NIRS) is used to monitor cerebral oxygenation during cardiac surgery. To date, reduced baseline cerebral NIRS values have been attributed to reduced cerebral blood flow primarily based on a significant positive correlation between left ventricular ejection fraction (LVEF) and baseline rSO measured with the INVOS 5100C oximeter. Reportedly, however, rSO, but not StO measured with the FORESIGHT Elite oximeter, correlated with LVEF.
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- A trial was conducted to compare the effects of continuing versus stopping single-pill combination tablets containing angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) in patients undergoing minor surgery.
- 106 patients were randomly assigned to either continue their medication (Group C) or withhold it (Group W) within 24 hours of surgery; their hemodynamic responses and clinical outcomes were analyzed.
- Results showed that continuing the medication led to higher instances of hypotension and greater medication needs during surgery, suggesting that it's better to withhold these drugs before the procedure for safer outcomes.
Article Synopsis
- Baseline cerebral regional saturation (rSO), measured in patients with cardiac and/or renal diseases using the INVOS 5100C, showed significant variability, highlighting a need for understanding its correlates.
- A study of 494 patients undergoing cardiovascular surgery found that high levels of preoperative B-type natriuretic peptide (BNP) were strongly associated with low baseline rSO levels.
- During surgery, rSO decreased significantly during cardiopulmonary bypass (CPB), but changes in rSO appeared to be more influenced by baseline conditions rather than intraoperative hemodynamic factors, suggesting that rSO readings are affected by tissue edema rather than just blood flow changes.
Objectives: To investigate an association between the preoperative plasma B-type natriuretic peptide (BNP) concentration and cerebral regional saturation (rSO) measured using the INVOS oximeter (Medtronic, Minneapolis, MN).
Design: A retrospective data analysis.
Setting: Single university hospital.