Evaluation and comparison of antifungal effect of voriconazole with nystatin on species derived from neoplastic patients undergoing maxillofacial radiotherapy.

Background: Radiotherapy is a common treatment for head-and-neck malignancies and causes complications such as oral candidiasis and the change of oral species from to . Voriconazole has acceptable antifungal effect. The aim of this study was to determine and compare the antifungal effect of nystatin with voriconazole on these species.

Comparison of oral candidiasis characteristics in head-and-neck cancer patients before and during radiotherapy.

Background: Patients undergoing head-and-neck radiotherapy are susceptible to colonization and infection. This study aimed to identify oral species type (ST), colony count (CC), and oropharyngeal candidiasis (OPC) in head-and-neck cancer patients, undergoing radiotherapy, before and 2 weeks after radiation.

Materials And Methods: In this quasi-experimental study, head-and-neck cancer patients undergoing radiotherapy (up to 6000 cGy) were recruited.

Comparison of the antifungal effect of voriconazole and fluconazole on oral candidiasis before and during radiotherapy.

Background: Head-and-neck radiotherapy can change oral species and cause candidiasis resistance to common antifungals by making the changes to the oral cavity environment. Voriconazole is a synthetic azole with extensive antifungal activity. The current study aimed at comparing the antifungal activity of fluconazole and voriconazole on species isolated from the oral cavity of patients undergoing head-and-neck radiotherapy.