Comparative efficacy of transdermal nitroglycerin and oral nifedipine in managing preterm labor: a systematic review and meta-analysis of randomized controlled trials.

Background: Preterm delivery is the leading cause of neonatal morbidity and mortality. This study performed a systematic review and meta-analysis to compare the efficacy of transdermal nitroglycerin and oral nifedipine in managing preterm labor.

Methods: A comprehensive search was conducted across multiple MEDLINE, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials for the randomized controlled trials comparing the effectiveness of nitroglycerin vs.

Leishmania infantum: prime boost vaccination with C-terminal extension of cysteine proteinase type I displays both type 1 and 2 immune signatures in BALB/c mice.

The aims of current study are to describe the immunogenicity and protective efficacy of prime boost vaccine using C-terminal extension (CTE) of cysteine proteinase type I of Leishmania infantum in BALB/c mice. Group I as vaccinated group primed with 100 microg of pcDNA-CTE and 3 weeks later boosted with combination of 30 microg rCTE, 50 microg of CpG and Montanide 720. Groups II and III were served as control groups.