Publications by authors named "Mahmut Ozden"
Aim: To examine the outcomes of microsurgery only versus combined microsurgery and embolization in treating cerebral arteriovenous malformations (AVM).
Material And Methods: A total of 62 patients (34 male and 28 female) with Spetzler-Martin grade 3 (n=44) and grade 4 (n=18) AVMs were examined. Thirty-seven patients were treated with a combination of microsurgery + embolization, whereas 25 patients were treated with microsurgery alone.
Aim: To define whether characteristics of fluorescein staining help to distinguish low grade gliomas intraoperatively.
Material And Methods: We studied 46 patients with supratentorial newly diagnosed noncontrast-enhancing LGGs removed by fluorescence guidance under the YELLOW 560 nm filter. Patients who were treated between July 2019 and 2022 were retrospectively analyzed.
Aim: To present our experience of 44 consecutive carotid endarterectomy procedures in 42 patients and assess the efficacy and success of ICG-VA in the localization of the plaque sites, extent of the arteriotomy, evaluation of the flow, and presence of thrombus after closure.
Material And Methods: This study was retrospectively designed, which included all the patients who underwent carotid stenosis operation between 2015 and 2019. ICG-VA was used in all procedures, and patients with available follow-up and full medical data were analyzed.
Background: To reveal whether pathological disc changes (vascularization, inflammation, disc aging and senescence as assessed with immunohistopathological CD34, CD68, brachyury and P53 staining densities respectively) are associated with the extent of disease (Pfirrmann grade) and lumbar radicular pain in patients with lumbar disc herniation. We selectively included a homogenous group of 32 patients (16 males and 16 females) with single-level sequestered discs who had disease stages between Pfirrmann grades I to IV and excluded patients with the complete collapse of the disc space to determine histopathological correlations of the disease more precisely.
Materials And Methods: Pathological assessments were performed on surgically excised disc specimens stored in a -80°C refrigerator.
Article Synopsis
- This study evaluates the effectiveness of a posterior-only surgical approach for treating non-pathological traumatic thoracolumbar fractures with spinal cord compression in 17 patients.
- Results showed that while all patients initially had some neurological deficit, 13 experienced improvement post-surgery, and there was a significant reduction in pain levels (mean VAS score dropped from 8.2 to 3.3).
- The findings suggest that the posterior-only method not only successfully addresses structural deformities but also allows for comprehensive treatment of spinal injuries in one surgical session.
Objective: To assess the utility of intraoperative indocyanine green video angiography (ICG-VA) during microsurgical resection of arteriovenous malformations (AVMs).
Methods: Data of the 24 patients, who were surgically treated for AVM using intraoperative ICG-VA, were reviewed retrospectively. Postoperative digital subtraction angiography (DSA) was performed in all patients before they regained consciousness and became fully awake, and the results were compared with those obtained with intraoperative ICG-VA.
Posterior reversible encephalopathy syndrome (PRES) is a rare neurologic disorder, having such common radiological findings as vasogenic edema and white matter changes in watershed areas. The clinic and radiological outcome may not be reversible in 10 to 20% of patients, like in the case of our patient. Here, we discuss the pathogenetic factors that are essential in developing PRES after posterior fossa surgery.
View Article and Find Full Text PDFAim: To investigate the external anatomy of the fourth ventricle and dorsal brainstem using morphometric data, which could be useful for preoperative surgical planning.
Material And Methods: Between January 2017 and December 2017, 42 fresh adult cadavers were investigated for the measurements of the cadaver brainstems and fourth ventricle, and they were recorded by photography. Measurements were evaluated according to body mass indexes (BMIs) of the patients.
Aim: Evidence suggests an association between MMP-9 functional gene polymorphisms and several tumors. The aim of this study was to investigate the possible role of single-nucleotide polymorphisms (SNP) at MMP-9 R279Q A/G, P574R G/C and R668Q G/A and R668Q (rs17577) genotypes with glial tumors in Turkey.
Material And Methods: The present series consisted of tissue samples obtained from 100 cancer-free controls and 100 patients who had undergone glial tumor resection from 2007 to 2011 at the Cerrahpasa Medical Faculty of Istanbul University.