Publications by authors named "Mahmudul Hasan Sikder"

Desalination ensures the provision of potable water to those living in coastal areas, thereby guaranteeing access to safe drinking water. Urbanization and industrialization pollute natural water sources with untreated and partially treated wastewater. International researchers have been searching for cost-effective and environmentally friendly solutions to the above-highlighted difficulties.

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Healthy skin reflects a healthy microbiome and vice versa. The contemporary society, marked by a sharp increase in skin irritation cases, has compelled researchers, dermatologists, and the cosmetics industry to investigate the correlation between skin microbiomes and the use of skincare products. Different cosmetics can change skin's normal flora to a varying degree -some changes can be detrimental, there are also instances where these alterations aid in restoring the skin microbiome.

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  • A study was conducted to evaluate stakeholders' awareness of heavy metal contamination in poultry feed in Sherpur district, Bangladesh, analyzing the presence of metals like lead, chromium, cadmium, and nickel.
  • The majority (90%) of stakeholders lacked knowledge about contamination, with chromium levels in one area significantly higher than another, while cadmium levels in samples exceeded EU limits.
  • The findings recommend implementing regular monitoring and developing better poultry feed formulations to address the health risks posed by heavy metal contamination.
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  • The study investigates the prevalence of certain pathogens in sheep, which can lead to various health issues like enteritis and infertility, with the aim of identifying risk factors and antimicrobial resistance.
  • Researchers collected and analyzed 408 fecal samples from sheep farms in Mymensingh and Sherpur districts using culture, biochemical tests, and molecular methods like PCR.
  • Results showed an 8.82% infection rate in individual sheep and a 66.70% rate in flocks, with younger sheep being more susceptible. Additionally, most isolates were resistant to several antibiotics but fully susceptible to gentamicin and ciprofloxacin, emphasizing the need for a One Health approach to address these zoonotic threats.
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The rapid emergence of antimicrobial resistance (AMR) in has reinforced its status as a foodborne pathogen of significant public health concern. Resistant is typically transferred to humans via the consumption of contaminated animal products, particularly poultry. The genes associated with antimicrobial resistance in spp.

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The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase producing (ESBL-E), poses a significant global health challenge as it frequently causes the failure of empirical antibiotic therapy, leading to morbidity and mortality. The - and -derived CTX-M genotype is one of the major types of ESBL. Mobile genetic elements (MGEs) are involved in spreading ESBL genes among the bacterial population.

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Objective: The study is aimed to understand the antibacterial sensitivity of native and Indian varieties of garlic () and ginger () crude extracts against multidrug-resistant (MDR) poultry pathogen ( and sp.).

Materials And Methods: Thin layer chromatography (TLC) is used to identify the target spices' bioactive antibacterial compounds.

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Background And Aim: The bovine industry is threatened by one of the most serious and deadly enteric diseases, calf diarrhea, particularly in developing nations like Bangladesh. In this context, bacterial resistance to antimicrobial drugs and its detrimental consequences have become a critical public health issue that is difficult to address globally. This study aimed to isolate and identify and spp.

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  • * Microplastics, which are less than 5 mm in size, can contain dangerous additives and contaminants, posing risks to both aquatic and terrestrial life, as well as humans, through bioaccumulation in the food web.
  • * The article reviews the sources and impact of biomedical waste and urges immediate action to manage this waste to mitigate the rising pollution from microplastics and protect human health and the environment.
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  • * The study aimed to determine the prevalence and identify risk factors for C. fetus infection in bulls, alongside examining the antimicrobial resistance of the isolates through a survey of 300 bulls in Bangladesh.
  • * Results indicated that 75% of the farms had bulls infected, with an 8.7% infection rate in individual bulls; natural service significantly raised infection odds, and half of the isolates were multidrug-resistant, underscoring the urgency for control measures like mandatory artificial insemination.
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Background: Plant triterpenoids are major sources of nutraceuticals that provide many health benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in many fruits and vegetables, which is highly investigated for its pharmacological effect and benefit to human health.

Purpose: This systematic review critically discussed the potential pharmacological benefits of lupeol and its derivatives as evidenced by various cellular and animal model studies.

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  • * Out of 330 diarrheal samples tested, the overall prevalence of the pathogen was found to be 31.5%, with higher rates in younger age groups, particularly children aged 0-5 years.
  • * A significant portion (27.3% and 31.2%) of the identified pathogens showed multidrug resistance, highlighting the need for effective measures to reduce the incidence and address contributing factors such as hygiene and animal exposure.
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Mounting evidence support the potential benefits of functional foods or nutraceuticals for human health and diseases. Black cumin ( L.), a highly valued nutraceutical herb with a wide array of health benefits, has attracted growing interest from health-conscious individuals, the scientific community, and pharmaceutical industries.

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Objective: In recent years, lead (Pb) has arisen as a foremost contaminant due to overpopulation, rapid industrialization, and expansion that could contaminate the human food chain. However, the correlation between the environmental contamination of Pb and its spatial transfer to the dairy products is still unmapped. In this paper, we intend to evaluate the concentration of environmental Pb and its spatial distribution in dairy feed and products in Narayangonj, a highly polluted district of Bangladesh.

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In order to elucidate involvement of cyclic AMP and intracellular Ca2+,[Ca2+]i, in the modulation of aqueous humour formation (AHF), we studied the effects of terbutaline, forskolin and 8-Br-cAMP in the isolated bovine eye. We also studied the interaction of cAMP on calcium signaling in cultured ciliary epithelial (CE) cells. Drug effects on AHF were measured by fluorescein dilution.

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Microplastics (MPs; <5 mm) are found in all aquatic environments. Due to harmful impacts, MPs pose a great threat to the aquatic ecology. Therefore, this review aims to provide an overview of the risk, bioavailability, and toxicity of MPs in aquatic organisms.

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Background And Aim: Global trend to remove the antibiotic growth promoter (AGP) from animals contributes to the exploration of successful measures to sustain production and reduces the intestinal diseases in the post-AGP era. Plant extracts, therefore, have been used to improve performance and intestinal health. Here, we conducted a study to evaluate the effects of neem () leaf extracts (NLE) as alternatives to AGPs in broiler chickens.

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  • * A total of 84 broiler and cockerel farms were sampled, and 40.5% were found positive for Campylobacter spp. through various identification methods, including PCR testing.
  • * Significant risk factors for infection included older sheds, older birds, large flock sizes, insufficient downtime, lack of disinfection, using rice husk as litter, and less farming experience, highlighting areas for intervention to reduce human campylobacteriosis.
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Background And Aim: Indiscriminate and injudicious use of antibiotics in layer farms is a common practice of Bangladesh for the compensation of Poor management practices and ignorance. Despite this scenario, there is no published documentation on antibiotic usage pattern and farm management practices in layer farms. This study was undertaken to understand the farmers' perspective in small-scale layer farms regarding antibiotics usage and farm management.

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Now-a-days, various types of antibiotics are being used worldwide in veterinary sector indiscriminately for promotion of growth and treatment of the livestock. Significant portions of antibiotics are released through milk of dairy animals unaltered and exert serious harmful effects on human health. This review evaluates and compare researches on antibiotic residues in milk in published literatures from Pubmed, CrossRef, CAB direct, DOAJ, JournalTOCs, AGRICOLA, ScientificGate, Electronic Journals Library, CAB abstracts, Global Health Databases, Global Impact Factor, Google Scholar, Park Directory of Open Access Journals, BanglaJOL and ISC E-Journals.

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Objective: This study aims at investigating the antibacterial potential of ethanolic extract of (common name: Green tea) and (common name: Neem) leaves on methicillin-resistant (MRSA) and shiga-toxigenic (STEC).

Materials And Methods: Fresh leaves were processed and extracted by 99% ethanol and reconstituted with 50% ethanol before testing. Disk diffusion and broth microdilution methods were used to determine zone diameter of inhibition (ZDI) and minimum inhibitory concentration (MIC), respectively.

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Background: Mycobacteria inhabit diverse niches and display high metabolic versatility. They can colonise both humans and animals and are also able to survive in the environment. In order to succeed, response to environmental cues via transcriptional regulation is required.

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This study describes how bkaR, a highly conserved mycobacterial TetR-like transcriptional repressor, regulates a number of nearby genes that have associations with branched-chain keto-acid metabolism. bkaR (MSMEG_4718) was deleted from the nonpathogenic species Mycobacterium smegmatis, and changes in global gene expression were assessed using microarray analysis and reporter gene studies. bkaR was found to directly control the expression of 10 genes in M.

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