Publications by authors named "Mahmoud Reza Azghani"

Background: Chronic low back pain due to manual lifting continues to be one of the significant common public health challenges in modern societies despite increased automation. While there are extensive studies on the biomechanics of lifting as associated with LBP, the role of unstable and time-varying dynamic loads, quite common in industrial lifting and daily life, remains elusive.

Objectives: The present study aimed to investigate the response of trunk muscles in subjects with chronic non-specific low back pain (CNLBP) while holding unstable dynamic loads.

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Background: In the most of previous experiments, intrathecal administration of stem cells (SCs) was seen in the management of neurogenic bladder (NGB) following contusion or complete transaction in the rodent model of spinal cord injury (SCI). Here, we aimed to investigate whether intra bladder wall autologous bone marrow mesenchymal SC (BM-MSCs) transplantation, as a minimally invasive method, could improve bladder dysfunctions after a chronic phase of hemi- and complete-transection SCI in a female rat model.

Material And Methods: A total of forty-two female Wistar rats were randomly divided into 6 groups (each in 7) and subjected to complete and incomplete spinal cord transection by a laminectomy at the T9 vertebral level.

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[Purpose] The aim of this study was to compare the effects of "McGill stabilization exercises" and "conventional physiotherapy" on pain, functional disability and active back flexion and extension range of motion in patients with chronic non-specific low back pain. [Subjects and Methods] Thirty four patients with chronic non-specific low back pain were randomly assigned to McGill stabilization exercises group (n=17) and conventional physiotherapy group (n=17). In both groups, patients performed the corresponding exercises for six weeks.

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Synopsis of recent research by authors named "Mahmoud Reza Azghani"

  • Mahmoud Reza Azghani's research primarily focuses on understanding the biomechanics of low back pain (LBP) and exploring innovative therapeutic approaches to address associated dysfunctions, particularly in individuals with chronic non-specific low back pain.
  • One of his notable studies investigates trunk muscle responses to unstable dynamic loads, highlighting the effects of varied lifting conditions on individuals suffering from LBP, thereby filling a gap in existing literature.
  • Additionally, Azghani has explored the application of stem cell therapy, demonstrating that intra-bladder wall transplantation of bone marrow mesenchymal stem cells can enhance urinary bladder function following spinal cord injuries in animal models, suggesting a minimally invasive treatment for neurogenic bladder dysfunction.