Cell free preparations of probiotics exerted antibacterial and antibiofilm activities against multidrug resistant .

The sharp increase in antibiotic resistance imposes a global threat to human health and the discovery of effective antimicrobial alternatives is needed. The use of probiotics to combat bacterial pathogens has gained a rising interest. Pathogenic is causative of multiple clinical syndromes such as diarrheal diseases, meningitis and urinary tract infections.

Recombinant production of omega-3 fatty acids by probiotic Escherichia coli Nissle 1917.

Omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have beneficial effects on human health. The probiotic bacterium Escherichia coli Nissle is unable to produce either EPA or DHA. Escherichia coli Nissle was transformed with the pfBS-PS plasmid carrying the EPA/DHA gene cluster, previously isolated from a marine bacterium.