Aspergillus nodules: Natural history and the effect of antifungals.

Background: Aspergillus nodules are classified as a subset of chronic pulmonary aspergillosis. The optimal management approach is not known as their natural evolution following biopsy, the rate of progression to chronic cavitary pulmonary aspergillosis (CCPA) and the effect of antifungal treatment have not been described.

Objectives: To describe the clinical course of patients diagnosed with Aspergillus nodules and the effect of antifungal treatment.