Publications by authors named "Mahmoud Abed El-Latif"
Article Synopsis
- - Nodding syndrome (NS) is a severe childhood epilepsy linked to autoimmune processes and caused primarily by the parasitic worm Onchocerca Volvulus, linked to blackfly bites.
- - Recent research indicates that certain genetic factors, including MIF gene polymorphisms and HLA associations, play a role in NS susceptibility and protection, with high-expression MIF potentially providing a protective effect.
- - Although the presence of the MIF gene variant indicates possible protection, elevated plasma MIF levels in NS patients suggest it may also contribute to harmful autoimmunity and neuroinflammation.
Nodding syndrome (NS) is a devastating and enigmatic childhood epilepsy. NS is accompanied by multiple neurological impairments and neuroinflammation, and associated with the parasite Onchocerca volvulus (Ov) and other environmental factors. Moreover, NS seems to be an 'Autoimmune Epilepsy' since: 1.
View Article and Find Full Text PDFHLA-B*15:539 differs from HLA-B*15:151 by two nucleotide substitutions.
View Article and Find Full Text PDF