Publications by authors named "Mahmoud A Nawwar"
Article Synopsis
- The study isolated a new compound called tamgermanitin along with two unknown polyphenolics and 18 known phenolics from the leaves of Myricaria germanica.
- The structures of these compounds were determined using advanced NMR and spectral analysis methods.
- The extract and tamgermanitin showed strong cytotoxic effects against liver, breast, and prostate cancer cell lines, suggesting potential for cancer treatment and warranting further research.
Article Synopsis
- Three ellagitannins and one disulfated flavonol were extracted from Reaumuria vermiculata L., along with characterizing 16 known compounds using advanced spectroscopy techniques.
- The antioxidant activity of the extract and the isolated compounds was tested using the ORAC method, showing strong potential.
- The extract and specific ellagitannins exhibited significant cytotoxic effects against various cancer cell lines, with IC₅₀ values below 2.4 μg/ml, indicating low resistance and high efficacy.
Leaves of Eugenia edulis contain the new polyoxygenated flavonoid derivatives, gossypetin-3,8-dimethyl ether-5-O-beta-glucoside; gossypetin-3,5-dimethyl ether, and myricetin-3,5,3'-trimethyl ether. In addition, ten known polyphenolics were also isolated and identified. All structures were established on the basis of chemical and spectral evidence, including ESI-MS and 13C NMR.
View Article and Find Full Text PDFThe new natural caffeoyl esters, 3,6-di-O-caffeoyl-(alpha/beta)-glucose and 1-O-caffeoyl-beta-xylose, together with the hitherto unknown natural tannin, 2,3-O-hexahydroxydiphenoyl-4,6-O-sanguisorboyl-(alpha/beta)-glucose, have been isolated from the aqueous alcohol aerial part extract of Rubus sanctus. Establishment of all structures was based on the chemical and spectral evidence, including ESI-MS and 2D NMR.
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