Publications by authors named "Mahmoud A Makki"
Article Synopsis
- Vitiligo affects 0.5 to 2% of the global population and existing treatments are not very effective; this study explored a new film-forming gel using 5 fluorouracil (5FU) to address this issue.
- The researchers used a specific design to evaluate how different ratios of hydroxypropyl methylcellulose (HPMC) and Zein in the gel impacted drug release, finding that higher HPMC increased 5FU release, while more Zein decreased it.
- Clinical tests showed that patients treated with the 5FU gel after laser treatment had better outcomes, including reduced JAK3 gene expression, indicating the gel's potential as an effective treatment for vitiligo.
Background: Laser treatment of vascular skin conditions is very useful option yet remains to be a very challenging task.
Aims: To evaluate the efficacy of 577-nm diode laser for treating facial telangiectasia.
Patients And Methods: Thirty patients with facial telangiectasia were included in this prospective study.