Publications by authors named "Mahmoud A Khalaf"

Twenty-eight fungal endophytes were recovered from the different parts of and screened for their Taxol producing potency. Among these isolates, AUMC14487 was reported as the potent Taxol producer (90.53 μg/l).

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Article Synopsis
  • Terminal sterilization of bone allografts using gamma radiation is necessary to lower infection risks, but it can compromise their mechanical properties.
  • This research investigates the effect of free radical scavengers, hydroxytyrosol (HT) and alpha lipoic acid (ALA), on the structural and chemical changes in gamma-sterilized cortical bone.
  • Results showed that using HT and ALA before gamma radiation helped maintain the chemical structure of bone, particularly the ratios of amide I and II and collagen cross-links, which were negatively affected by the radiation treatment.
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Gamma radiation sterilization is the method used by the majority of tissue banks to reduce disease transmission from infected donors to recipients through bone allografts. However, many studies have reported that gamma radiation impairs the structural and mechanical properties of bone via formation of free radicals, the effect of which could be reduced using free radical scavengers. The aim of this study is to examine the radioprotective role of hydroxytyrosol (HT) and alpha lipoic acid (ALA) on the mechanical properties of gamma-sterilized cortical bone of bovine femur, using three-point bending and microhardness tests.

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Background And Aim: Drinking water of poor microbiological quality contains high percentages of microbes causing outbreaks of mainly coliform-related diseases. These microbes could be controlled by many hygienic standards including disinfection, but disinfectants misuse causes the developing of disinfectant-resistant strains. The present study aimed to investigate drinking water bacterial profile, determine chlorine-resistant strains, and statistically correlate that with the used disinfectant and disinfection process variables.

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Gibberellic acid (GA) production from milk permeate was studied by 28 mutants of Fusarium moniliforme, among which mutant gamma-14 was selected as the best producer. Experiments were carried out in shaker flasks and fermentative process was analyzed with free and immobilized cells. Immobilization of mutant gamma-14 cells onto loofa sponge discs was studied with respect to the optimization of the incubation temperature, initial pH, inoculum size (number of discs) and its reusability for GA production.

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The potential of Aspergillus niger fungus and Spirogyra sp., a fresh water green algae, was investigated as a biosorbents for removal of reactive dye (Synazol) from its multi component textile wastewater. The results showed that pre-treatment of fungal and algal biomasses with autoclaving increased the removal of dye than pre-treatment with gamma-irradiation.

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