Chitosan adorned with ZIF-67 on ZIF-8 biocomposite: A potential LED visible light-assisted photocatalyst for wastewater decontamination.

The current investigation has utilized a simple and constructive stratified method to synthesize a binary (Cs/Z-8: chitosan (Cs) and zeolitic imidazolate framework-8 (Z-8)) and ternary Cs/Z-8/Z-67 (Z-67: ZIF-67) biocomposites at room temperature. A certain amount of Cs/Z-8 (0.05, 0.

Nanovibrational Stimulation of Mitigates Surface Adhesion by Altering Cell Membrane Potential.

Mechanical forces shape living matter from the macro- to the microscale as both eukaryotic and prokaryotic cells are force wielders and sensors. However, whereas such forces have been used to control mechanically dependent behaviors in mammalian cells, we lack the same level of understanding in bacteria. Surface adhesion, the initial stages of biofilm formation and surface biofouling, is a mechanically dependent process, which makes it an ideal target for mechano-control.

The effect of escape room clinical evaluation method on satisfaction, learning, and preparedness to practice as interns of nursing students: A quasi-experimental quantitative study.

Background: Clinical evaluation utilizing the escape room game is recognized as a novel method for assessing the team-oriented performance of learners. It is a tool for evaluating teamwork skills in clinical settings, which can boost student motivation and learning. This study aimed to investigate the effect of clinical evaluation through escape rooms and feedback provision through the PEARLS (promoting excellence and reflective learning in simulation) approach on pre-internship nursing students' satisfaction, learning, and preparedness to practice as interns.

Bovine and Ovine Teeth as a Substitute for the Human Teeth: An Experimental Study.

Statement Of The Problem: Although various kinds of research have been conducted to compare the physical and chemical properties of dentin and enamel in animal and human samples, proving the ability of animal dentin material as a good substitute for human specimens is always a challenge for experimental studies.

Purpose: The aim of the present study is to investigate whether the changes in the dentin microhardness of animal samples are similar to those of human samples or not.

Materials And Method: In this study, sixty single-rooted human, bovine, and ovine teeth (n=20 in each group) were decoronated at CEJ.

Green and environmentally friendly architecture of starch-based ternary magnetic biocomposite (Starch/MIL100/CoFeO): Synthesis and photocatalytic degradation of tetracycline and dye.

The presence of tetracycline and dye as organic contaminants has led to the poisoning of wastewater. The aim of this study is to synthesize a novel biocomposite material by decorating natural starch polymer granules with metal-organic framework (MIL100) and cobalt ferrite magnetic (CoFeO) nanoparticles. The synthesized ternary magnetic biocomposite (Starch/MIL100/CoFeO) was used for the photocatalytic degradation of methylene blue (MB) and tetracycline (TCN) using LED visible light.

Synthesis, Characterization, Molecular Docking, and Investigation of Antibacterial Properties of New Derivatives of 1-H-Phenanthro [9,10-d] Imidazole.

In this study, several imidazole derivatives in one pot multicomponent reaction from various aldehydes 1(a-z), 9,10-phenanthrenequinone, or benzyl (2), and ammonium acetate (3) were synthesized in the presence of acetic acid (AcOH) under reflux conditions at 120 °C. Also, the photochromic properties of synthesized compounds were investigated in AcOH as a solvent under laboratory conditions at a temperature of 120 °C. Moreover, the antibacterial activity of the synthesized compounds was investigated.

Pancreatic anastomosis training models: Current status and future directions.

Postoperative pancreatic fistula (POPF) is a major cause of morbidity and mortality after pancreatoduodenectomy (PD), and previous research has focused on patient-related risk factors and comparisons between anastomotic techniques. However, it is recognized that surgeon experience is an important factor in POPF outcomes, and that there is a significant learning curve for the pancreatic anastomosis. The aim of this study was to review the current literature on training models for the pancreatic anastomosis, and to explore areas for future research.

The design and characterisation of sinusoidal toolpaths using sub-zero bioprinting of polyvinyl alcohol.

Sub-zero (°C) additive manufacturing (AM) systems present a promising solution for the fabrication of hydrogel structures with complex external geometry or a heterogeneous internal structure. Polyvinyl alcohol cryogels (PVA-C) are promising tissue-mimicking materials, with mechanical properties that can be designed to satisfy a wide variety of soft tissues. However, the design of more complex mechanical properties into additively manufactured PVA-C samples, which can be enabled using the toolpath, is a largely unstudied area.

Heterogeneous MIL-88A on MIL-88B hybrid: A promising eco-friendly hybrid from green synthesis to dual application (Adsorption and photocatalysis) in tetracycline and dyes removal.

Herein, the green synthesis of heterogeneous dual functional MIL88A-on-MIL88B hybrids (MIL: Materials InstituteLavoisier) with different amounts of MIL88B compared to MIL88A, including 1:2, 1:1, and 2:1, has been carried out. The photocatalytic degradation of tetracycline and adsorption of tetracycline and dyes (Direct Red 80, Direct Red 23, Acid Blue 92, and Reactive Orange 14) were investigated. Although the ratio of MIL88A-on-MIL88B (1:1) hybrid displayed the best activity, there is a slight difference in the photocatalytic performance of the other mass ratios studied.

Evaluating Serum Proteome in Women with Obsessive-Compulsive Disorder/Bipolar Disorder Compared to Pure Obsessive- Compulsive Disorder Subjects and Healthy Controls.

Objectives: The present study aimed to evaluate the serum proteome of women with obsessive-compulsive disorder (OCD)/bipolar disorder (BP) compared to pure OCD subjects and healthy controls.

Materials & Methods: Serum proteome of women with OCD/BP, pure OCD individuals, and healthy controls were subjected to 2DE-based proteomics accompanied with MALDI-TOF-TOF mass spectrometry. Further evaluation of the identified protein spots with the significance of p<0.

Cell-Effective Transition-State Analogue of Phenylethanolamine -Methyltransferase.

Phenylethanolamine -methyltransferase (PNMT) catalyzes the -adenosyl-l-methionine (SAM)-dependent methylation of norepinephrine to form epinephrine. Epinephrine is implicated in the regulation of blood pressure, respiration, Alzheimer's disease, and post-traumatic stress disorder (PTSD). Transition-state (TS) analogues bind their target enzymes orders of magnitude more tightly than their substrates.

Aldehyde-Based Inhibitors of the Peptidoglycan O-Acetylesterase Ape.

The O-acetylation of the muramic acid residues in peptidoglycan (PG) is a modification that protects the bacteria from lysis due to the action of lysozyme. In Gram-negative bacteria, deacetylation is required to allow lytic transglycosylases to promote PG cleavage during cell growth and division. This deacetylation is catalyzed by O-acetylpeptidoglycan esterase (Ape) which is a serine esterase and employs covalent catalysis via a serine-linked acyl enzyme intermediate.

Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering.

Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover after damage. A clinically acceptable treatment to promote CNS functional recovery and regeneration is currently unavailable. According to recent studies, injectable hydrogels as biodegradable scaffolds for CNS tissue engineering and regeneration have exceptionally desirable attributes.

Enhanced sciatic nerve regeneration with fibrin scaffold containing human endometrial stem cells and insulin encapsulated chitosan particles: An in vivo study.

Background: Based on recent advances in tissue engineering and stem cell therapy in nervous system diseases treatments, this study aimed to investigate sciatic nerve regeneration using human endometrial stem cells (hEnSCs) encapsulated fibrin gel containing chitosan nanoparticle loaded by insulin (Ins-CPs). Stem cells and also Insulin (Ins), which is a strong signaling molecule in peripheral nerve regeneration, play an important role in neural tissue engineering.

Methods: The fibrin hydrogel scaffold containing insulin loaded chitosan particles was synthesized and characterized.

Impact of on various characteristics of tomatoes during nickel nitrate stress under aeroponic and greenhouse conditions.

As an essential nutrient for plant growth, nickel's (Ni) requirement is very low, and its augmented level causes environmental pollution and toxicity. Being a root endophytic fungus, () can be beneficial to many plants under stress and non-stress conditions, particularly in terms of their improved growth performance. , as evidenced, enhances tolerance and resistance in most plants once they experience a range of stresses caused by biotic and abiotic factors, e.

Anti-inflammatory effect of green photobiomodulation in human adipose-derived mesenchymal stem cells.

Photo biomodulation (PBM) as a non-invasive and safe treatment has been demonstrated the anti-inflammatory potential in a variety of cell types, including stem cells. However, further investigations using different laser parameters combined with more accurate methods such as quantitative measurement of inflammatory gene expression at the mRNA level are still necessary. The aim of this study was to evaluate the effect of 532 nm green laser on cell proliferation as well as expression of inflammatory genes in human adipose-derived mesenchymal stem cells (hADMSCs) using RNA sequencing (RNA-seq) technique and confirmatory RT-PCR.

Cancer, Fertility and Me: Developing and Testing a Novel Fertility Preservation Patient Decision Aid to Support Women at Risk of Losing Their Fertility Because of Cancer Treatment.

Background: Women with a new cancer diagnosis face complex decisions about interventions aiming to preserve their fertility. Decision aids are more effective in supporting decision making than traditional information provision. We describe the development and field testing of a novel patient decision aid designed to support women to make fertility preservation treatment decisions around cancer diagnosis.

The sweet wormwood essential oil and its two major constituents are promising for a safe control measure against fall webworm.

The fall webworm, Hyphantria cunea (Drury), is a harmful polyphagous global defoliator. The major chemical components of Artemisia annua essential oil (EO) was found to contain (±)-camphor (16.42%), 1,8-cineole (6.

Protective effects of extract against scopolamine-induced behavioral disturbances and brain oxidative stress in rats.

Ethnopharmacological Relevance: Alzheimer's disease (AD) as the most common type of dementia, is affecting the life of many senior individuals around the world. Vinca Waldst. & Kit.

Visible-Light-Driven Reduced Graphite Oxide as a Metal-Free Catalyst for Degradation of Colored Wastewater.

Reduced graphite oxide (rGO)-based materials have demonstrated promising potential for advanced oxidation processes. Along with its distinctive 2D characteristics, rGO offers the prospect of catalytic degradation of various kinds of organic pollutants from aqueous environments. The practical application of rGO as a metal-free catalyst material to promote the Fenton reaction depends on the degree of rGO reduction.

Drug delivery system for controlled release of empagliflozin from alginate-chitosan nanocarrier system.

A biocompatible nanocarrier system was prepared in this research through the reaction of calcium alginate (CA) with chitosan (CS). The structure of developed nanocarriers (CS-CA) was characterized by thermogravimetric analysis (TGA), Fourier transforms infrared (FT-IR) spectroscopy, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) atomic force microscopy (AFM), and transmission electron microscopy (TEM). Swelling properties of CS-CA and CA, and their ability for loading and in vitro release of empagliflozin (EMP) were also investigated.

Advanced approaches to regenerate spinal cord injury: The development of cell and tissue engineering therapy and combinational treatments.

Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is hampered through a myriad of devices counting on the damaged myelin, inflammation, glial scar, and defective inhibitory molecules. Unfortunately, an effective treatment to completely repair SCI and improve functional recovery has not been found.

Improving motor neuron-like cell differentiation of hEnSCs by the combination of epothilone B loaded PCL microspheres in optimized 3D collagen hydrogel.

Spinal cord regeneration is limited due to various obstacles and complex pathophysiological events after injury. Combination therapy is one approach that recently garnered attention for spinal cord injury (SCI) recovery. A composite of three-dimensional (3D) collagen hydrogel containing epothilone B (EpoB)-loaded polycaprolactone (PCL) microspheres (2.

Adsorption of azo dyes by a novel bio-nanocomposite based on whey protein nanofibrils and nano-clay: Equilibrium isotherm and kinetic modeling.

Excessive discharge of synthetic azo dyes into the aquatic ecosystem is a global concern. Here, we develop a green approach to remediate dye pollutants by fabricating an easily separable bio-nanocomposite, based on nanofibrils from whey protein concentrate together with montmorillonite. The nanocomposite was characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and surface area analysis.

Preparation of novel and highly active magnetic ternary structures (metal-organic framework/cobalt ferrite/graphene oxide) for effective visible-light-driven photocatalytic and photo-Fenton-like degradation of organic contaminants.

Herein, MIL-101(Fe), CoFeO, novel binary (MIL-101(Fe)/CoFeO, MIL-101(Fe)/GO and CoFeO/GO), and ternary (MIL-101(Fe)/CoFeO/(3%)GO and MIL-101(Fe)/CoFeO/(7%)GO) magnetic composites based upon the MIL-101(Fe) were synthesized. The XRD, FESEM, TEM, EDX, BET-BJH, FTIR, VSM, DRS, PL, EIS and other electrochemical analyses were applied to characterize samples. The MIL/CoFeO/(3%)GO demonstrated the best performance compared to other samples for visible light photocatalytic and photo-Fenton-like degradation of Direct Red 23 (DtR-23), Reactive Red 198 (ReR-198) dyes as well as Tetracycline Hydrochloride (TC-H) antibiotic.