Primary vulval melanoma and genital lichen sclerosus.

Background: Lichen sclerosus (LS) is a chronic, inflammatory skin disease with a predilection for the genitalia. Although, the association between squamous cell cancer and genital LS is well established, a link with genital melanoma has not been thoroughly explored. However, we have recently published a case series of penile melanoma where 9/11 (82%) of patients seen over a 10 year period with penile melanoma were retrospectively found to have histological and/or clinical evidence of genital LS on review.

The significance of microbiopsies in cytological smears.

Background: The role of fine needle aspiration cytology (FNAC) in the diagnosis of malignant lesions is well documented. Conventionally obtained fine needle aspiration (FNA) smears frequently contain well preserved viable intact tissue fragments (microbiopsies).

Aims: The present study was aimed at evaluating the microbiopsies and carrying out further cyto-histopathologic correlation in order to assess what additional information they could provide.

Giant Cell Fibroblastoma: A Case Report.

Giant cell fibroblastoma is a rare intermediate grade soft tissue tumor of childhood which characteristically occurs in males during the first decade of life. It has high incidence of local recurrence but metastasis has never been reported. Giant cell fibroblastoma merits attentive interpretation as they have been misdiagnosed as sarcoma in the past leading to erroneous remedies.

Adenomatoid tumour of testis.

Adenomatoid tumour is a rare neoplasm of mesothelial origin commonly seen in male and female genital tract. In this case report, the authors present a case of adenomatoid tumour in a 35-year-old male who presented with 1-year history of scrotal swelling. A clinical diagnosis of testicular neoplasm was made but final diagnosis of adenomatoid tumour was made after excisional biopsy.

Multicystic renal dysplasia: a diagnostic dilemma.

A 3-year-old male child had left-sided abdominal lump for 4 months. Radiological examination revealed a cystic mass in the left kidney. A tentative diagnosis of multicystic nephroma was made on clinical and radiological examination.

Kaposi sarcoma presenting as dermal nodule.

Kaposi sarcoma (KS) is a rare tumour caused by human herpes virus 8. It is a systemic disease which can present with skin lesions with or without internal involvement. We are presenting here a case of classic subtype of KS in a 60-year-old male who presented with a 4-month history of nodular lesion over right hand.

Congenital dyserythropoietic anaemia type II: a rare entity.

Congenital dyserythropoietic anaemias (CDAs) are a group of rare hereditary disorder characterised by ineffective erythropoiesis and dyserythropoiesis. Among the three variants, type II is the most common. The authors are presenting two cases of CDA type II in two sisters.