Publications by authors named "Mahey Reeta"
Background: There is a paucity of data on the optimal threshold of oestradiol (E2) levels required for successful implantation as this is a valid question to be answered, considering that significant number of fertilisation cycles are deferred for FET cycles.
Aim: The aim of this study is to investigate the serum E2 levels before starting exogenous progesterone in artificial autologous frozen thawed embryo transfers on pregnancy outcomes.
Settings And Design: This was a cohort study wherein clinical data of 213 artificial autologous programmed hormone-regulated frozen embryo transfer (HR-FET) cycles were collected.
Background: Females undergoing laparoscopic gynaecological surgeries have a high incidence of postoperative nausea and vomiting. Apart from the established risk factors, hormonal, psychological, genetic and ethnic factors may also contribute to postoperative nausea and vomiting. This study aimed to evaluate the relationship between preoperative anxiety and serum oestrogen level with postoperative nausea and vomiting in patients undergoing diagnostic laparoscopy - hysteroscopy for infertility.
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- The study focuses on four cases of rare ectopic pregnancies occurring at the utero-tubal junction, highlighting the potential for severe maternal complications if these cases go undetected.
- All four cases had different presentations, requiring distinct approaches for diagnosis, where initial 2D transvaginal scans were inadequate, and 3D transvaginal scans provided better localization of the gestational sacs.
- The findings emphasized the importance of 3D imaging in managing these complex ectopic pregnancies and introduced a diagnostic algorithm and management strategies tailored to each case type.
Purpose: To determine the status of physical fitness, reproductive abnormalities, QOL and epilepsy associated stigma in women with epilepsy (WWE) and their association with ASM therapy and seizure frequency.
Methods: This cross-sectional study included WWE of reproductive age (18-50 years) on antiseizure medications (ASMs) for at least three months before enrolment. Physical fitness was assessed using International Physical Activity Questionnaires (IPAQ) and Body composition analysis.
Article Synopsis
- - The study focuses on assessing the effectiveness of two metrics, the visceral adiposity index (VAI) and lipid accumulation product (LAP), in identifying metabolic health in women with polycystic ovary syndrome (PCOS), who are at risk of conditions like diabetes and cardiovascular disease due to insulin resistance and hyperandrogenism.
- - The research involved evaluating 200 women with PCOS, categorizing them into metabolically healthy (MH-PCOS) and unhealthy (MU-PCOS) groups, and examining the correlation of VAI and LAP with various metabolic and endocrine markers.
- - Results indicated that both VAI and LAP are reliable predictors for distinguishing between MH-PCOS and MU-PCOS, demonstrating high sensitivity levels, which
Article Synopsis
- * Results showed that the most common genotype among fertile women was GG (Ser/Ser), while infertile women had an equal distribution of all genotypes, and there were no significant differences in IVF performance metrics like ovarian response and live birth rates among the different genotype groups.
- * The study concludes that while the GG genotype may have a lower risk of poor egg yield, the overall impact of FSH-R polymorphisms on ART outcomes is
Article Synopsis
- The study aimed to evaluate if combining a GnRH agonist with hCG trigger enhances oocyte maturation and high-grade embryos in IVF cycles using GnRH antagonists.
- It included 100 patients, who were randomly assigned to receive either the dual trigger (GnRH agonist + hCG) or just hCG; results showed that the dual trigger group had significantly more mature oocytes and higher-quality embryos.
- Although fertilization and clinical pregnancy rates were similar between the two groups, the dual trigger led to higher LH levels and allowed for more embryo cryopreservation, potentially increasing chances of live births.
Background The World Health Organization's call for elimination of cervical cancer envisages 70% screening coverage of women aged 35 and 45 years by an effective test. In India, this target seems unrealistic as awareness and access to cancer prevention services are poor. However, the institutional delivery rate is now >80%.
View Article and Find Full Text PDFBackground: The purpose of the current study was to evaluate patient-oriented strategies encompassing individualized oocyte number (POSEIDON) criteria, validate stratification of low prognosis women, and prognosticate their reproductive potential in terms of cumulative live birth rate (CLBR) in Indian women.
Methods: Out of 4048 women who underwent IVF/ICSI, 3287 women met the criteria for final evaluation of CLBR. They criteria were divided into (a) group 1a as cases with <4 oocytes retrieved and 1b with 4-9 oocytes retrieved; (b) group 2a as cases with <4 oocytes retrieved and 2b with 4-9 oocytes retrieved; (c) group 3 (<35 years, AMH <1.
This case report highlights the diagnostic dilemma and therapeutic challenges encountered while managing adolescent girls with progressive dysmenorrhoea and management of Robert's uterus. Two girls aged 20 years and 13 years presented with severe progressive dysmenorrhoea. In the first case, laparoscopy revealed juvenile cystic adenomyoma (JCA) of 3 cm × 3 cm on the left side anteroinferior to the round ligament.
View Article and Find Full Text PDFBackground: Optimal incubation period for oocyte competence remains contentious despite intracytoplasmic sperm injection(ICSI) being in practice for 34 years. Dilemma exists as the current literature favors both early and delayed denudation with equivocal results. With ever-rising demand for the procedure this conundrum continues to plague the clinical outcomes.
View Article and Find Full Text PDFObjectives: Assisted Reproductive Technology (ART) has made great strides in the past forty-years, but no medical treatment comes without side effects. Despite several studies reporting high incidences of perinatal complications, the association is inconclusive. Also, the effect of racially and ethnically distinguished Asian population undergoing ART on perinatal outcomes is not well studied.
View Article and Find Full Text PDFAnti-Mullerian hormone (AMH) is one of the direct indicators of follicular pool but no standard cutoff has been defined for diagnosis of polycystic ovary syndrome (PCOS). The present study evaluated the serum AMH levels among different PCOS phenotypes and correlated the AMH levels with clinical, hormonal, and metabolic parameters among Indian PCOS women. Mean serum AMH was 12.
View Article and Find Full Text PDFBackground: Herniation of ovaries and Mullerian structures into inguinal canal is usually reported in infants and is rare among adults. We are presenting a rare case of Mullerian agenesis and Turner mosaic syndrome with tubo-ovarian inguinal hernia.
Case Presentation: A 17-year-old girl presented with complaints of primary amenorrhea, phenotypical features of Turner syndrome with left inguinal hernia and severe hypertension.
Neerja Bhatla Human Epididymis protein 4 (HE4) is expressed in ovarian cancer. Preoperative serum testing is still not widely available. This pilot study aimed to investigate the magnitude of expression of HE4 in tissue sections of serous epithelial ovarian carcinoma, its correlation with clinical outcome, and the feasibility of HE4 immunohistochemistry as a prognostic marker.
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- The study aimed to compare glycemic parameters from continuous glucose monitoring (CGMS) between women with normal glucose levels and those diagnosed with early gestational diabetes mellitus (GDM) based on mild blood sugar elevations.
- It included 87 women in their first trimester, finding that many diagnosed with GDM had elevated fasting or post-load glucose levels, often leading to misdiagnosis when using a higher fasting glucose cutoff.
- The results indicated that relying solely on a higher fasting glucose threshold could overlook about 71% of women with GDM, who exhibited significantly different glycemic profiles compared to those with normal glucose levels.
Article Synopsis
- - The study analyzed pregnancy outcomes in women aged 20-45 who conceived using oocyte donation (102 women) compared to a control group of spontaneously conceived pregnancies (306 women) to determine if complications stemmed from the oocyte donation itself or other factors.
- - Results showed that women using donor oocytes had a higher average age (35.13 years) and experienced significantly higher rates of pregnancy complications, such as pregnancy-induced hypertension (33.33% vs. 7.18%) and gestational diabetes (34.31% vs. 9.47%).
- - The findings suggest that oocyte donation increases risks for miscarriage, hypertensive disorders, and gestational diabetes mellitus, indicating it should be regarded as an
Objective: To investigate the relationship between progesterone (P4) levels on the day of hCG trigger and IVF outcomes.
Methods: This is a retrospective analysis of IVF cycles from January-2013 to December-2019 from a single center. Women (21-39 years) submitted to IVF treatment for various infertility factors were included, while donor oocyte cycles and cancelled cycles were excluded from the study.
Article Synopsis
- A study was conducted to compare maternal outcomes between assisted reproductive techniques (ART) and spontaneous pregnancies in a large Asian population, revealing significant differences in complications.
- The research found that IVF-conceived pregnancies had a higher risk of gestational diabetes and pregnancy-induced hypertension, as well as an increased likelihood of cesarean deliveries.
- The conclusion emphasizes the need for patients undergoing ART to receive counseling about these potential risks, as ART pregnancies are considered high-risk compared to spontaneous ones.
Background: To evaluate the maternal and perinatal outcome in pulmonary tuberculosis cases as compared to low risk pregnancies in a tertiary referral hospital.
Methods: A total of 15 cases of pulmonary tuberculosis over a period of two years who delivered in our unit was studied in the retrospective study. The maternal and perinatal outcome in them was compared with 191 low risk pregnancies who delivered at the same time in the hospital after taking into account inclusion and exclusion criteria.
Objectives: This prospective clinical trial was conducted to assess serum bile acids (BA) levels in women with intrahepatic cholestasis of pregnancy (ICP) compared to both pregnant and non-pregnant controls; and evaluate perinatal outcome in relation to bile acid levels. A scoring is proposed based on biochemical markers to optimize management in ICP cases.
Materials And Methods: Serum bile-acids(BA) were assessed in 71 intrahepatic-cholestasis of pregnancy(ICP) cases (group-I), versus 50 pregnant (group-II) and 35 non-pregnant (group-III) controls.
Aims/introduction: We aimed to evaluate and compare continuous glucose monitoring system (CGMS)-based glycemic parameters in women in early pregnancy (<20 weeks of gestation) who were classified as: (i) gestational diabetes mellitus (GDM) by the International Association of Diabetes and Pregnancy Study Groups (IADPSG), but normoglycemia by alternate (UK National Institute for Health and Care Excellence, Canadian Diabetes Association and Diabetes in Pregnancy Study group of India) criteria; and (ii) normoglycemia by both (IADPSG and alternate) criteria.
Material And Methods: In this cross-sectional study, eligible women underwent standard 75-g oral glucose tolerance test, followed by the placement of a CGMS. Glycemia-related parameters were calculated using the standard approach for CGMS data in pregnancy.
Article Synopsis
- The study investigated the knowledge, attitudes, perceptions, and concerns of pregnant and lactating women about COVID-19 vaccination through a cross-sectional survey.
- Most participants (90%) supported vaccination, with awareness that both pregnant (72.2%) and lactating women (65.2%) are eligible, though willingness to pay for the vaccine varied by socioeconomic status.
- Key factors causing vaccine hesitancy included fears about long-term effects on the fetus (58.6%) and the quick development of the vaccine without adequate trials involving this demographic (53.6%).