Publications by authors named "Mahesh Rao"

Dr. Suhas Vitthal Mapuskar was an Indian doctor and a social activist who revolutionized rural sanitation practices way before it became a national priority. Nicknamed affectionately as "Dr.

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In India, amphidiploid (AABB, 2n=36) is a significant oilseed crop, but its small gene pool limits its ability to develop traits of higher breeding and economic value. Through interspecific hybridization from various lines of the progenitor species, resynthesized (RBJ) can provide breeders with additional resources for creating genetically diverse stress-tolerant and high-yielding cultivars. Three accessions and eight accessions were crossed in this study to develop 33 synthetic lines.

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Linseed, has been a source of natural fiber for textile industries since its domestication. However, despite being the potential source of trait reservoir, the use of Linum wild genetic resources for the improvement of economic traits are not exploited widely. This is mainly due to the degree of genetic divergence that exists among the interspecific ecotypes causing crossability issues.

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Article Synopsis
  • Sclerotinia sclerotiorum is a significant phytopathogen that causes Stem rot disease in Brassica crops, leading to decreased yields and oil quality, particularly in rapeseeds and Indian mustard.
  • The pathogen's hemibiotrophic nature and ability to persist in soil complicate management through traditional farming practices, making it essential to explore alternative strategies.
  • Recent advancements in omics technologies have identified various molecular components involved in the disease process, which may be utilized to enhance resistance in susceptible Brassica cultivars.
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  • Cucumber (Cucumis sativus L.) is being researched for its potential to develop haploids and doubled haploids, which are key for creating pure inbred lines and speeding up plant breeding processes.
  • This study successfully induced haploid plants using gamma-irradiated pollen across different cucumber genotypes, focusing on the effects of varying doses of irradiation on plant development.
  • The findings highlight that using this method can significantly increase haploid production, which can improve genetic advancements and contribute to better agricultural practices and food security.
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The study presents the first to characterize novel Erucastrum canarianse Webb and Berthel (or Can) sterile cytoplasm-based CMS lines in Indian cauliflower (Brassica oleracea var. botrytis L.) and investigating their commercial suitability.

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  • Drought significantly affects crop yields, particularly in India where 24% of Indian mustard is grown under rainfed conditions, necessitating the development of drought-tolerant varieties.
  • The study involved creating introgression lines from B. carinata to B. juncea and evaluating their performance for seed yield and related traits under both rainfall-dependent and irrigated conditions across multiple environments.
  • A total of 29 QTLs associated with drought tolerance were identified, with a notable contribution from B. carinata, particularly on the B genome, highlighting several candidate genes linked to stresses and paving the way for future improvements in drought resilience in mustard crops.
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The haploid and doubled haploid plants serve as valuable tools for breeders due to their ability to expedite the mapping of genes of agronomic importance, as well as accelerate the breeding cycle for generation of novel hybrids and improved homogenous varieties. Successful anther/microspore culture largely depends on the use of microspores at appropriate developmental stages at the time of culture, which can be specific for each plant species and genotype. In the present study, we described the visible morphological characteristics of flower buds and anthers at different developmental stages to identify the optimal microspore stage within the anther/buds of two pepper hybrids, Indra and Lakshmi.

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Background: A goal of developmental genetics is to identify functional interactions that underlie phenotypes caused by mutations. We sought to identify functional interactors of Vsx2, which when mutated, disrupts early retinal development. We utilized the Vsx2 loss-of-function mouse, ocular retardation J (orJ), to assess interactions based on principles of positive and negative epistasis as applied to bulk transcriptome data.

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Article Synopsis
  • Every year, a significant portion (30-50%) of crops is affected by fungal and bacterial diseases, prompting the need for safer and cost-effective alternatives to toxic chemical treatments.
  • Recent research highlights the potential of zinc oxide nanoparticles (ZnO NPs), particularly those synthesized from Terminalia bellerica (Tb-ZnO NPs), as both nanofungicides and nanofertilizers for controlling pathogens like Alternaria brassicae in crops such as Brassica juncea.
  • Experiments indicated that a concentration of 200 ppm of Tb-ZnO NPs not only enhances plant growth parameters but also improves seed yield and oil content while achieving up to 70% disease control, underlining the beneficial link between nutrient
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Wild species are weedy relatives and progenitors of cultivated crops, usually maintained in their centres of origin. They are rich sources of diversity as they possess many agriculturally important traits. In this study, we analysed 25 wild species and 5 U triangle species of for their potential tolerance against heat and drought stress during germination and in order to examine the early seedling stage.

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White mold commonly known as Sclerotinia sclerotiorum causes stem rot disease and has emerged as one of the major fungal pathogens of oilseed Brassica across the world. In the present study, consistently virulent S. sclerotiorum isolate "ESR-01" was sequenced and an assembly size of ~ 41 Mb with 328 scaffolds having N50 of 447,128 was obtained.

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Crop wild relatives (CWRs) are weedy and wild relatives of the domesticated and cultivated crops, which usually occur and are maintained in natural forms in their centres of origin. These include the ancestors or progenitors of all cultivated species and comprise rich sources of diversity for many important traits useful in plant breeding. CWRs can play an important role in broadening genetic bases and introgression of economical traits into crops, but their direct use by breeders for varietal improvement program is usually not advantageous due to the presence of crossing or chromosome introgression barriers with cultivated species as well as their high frequencies of agronomically undesirable alleles.

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Nanotechnology has gained popularity in recent years owing to its established potential for application and implementation in various sectors such as medical drugs, medicine, catalysis, energy, material, and plant science. Nanoparticles (NPs) are smaller in size (1-100 nm) with a larger surface area and have many fruitful applications. The extraordinary functions of NPs are utilized in sustainable agriculture due to nano-enabled products, e.

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Cadmium (Cd) is a hazardous heavy metal, toxic to our ecosystem even at low concentrations. Cd stress negatively affects plant growth and development by triggering oxidative stress. Limited information is available on the role of iron (Fe) in ameliorating Cd stress tolerance in legumes.

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Background: Chemomechanical caries removal has been a new leaf for caries excavation in this ultraconservative era of dentistry. BRIX3000 & Carie Care are papain based gel formulations while Smart Burs are polymer burs with self limiting ability.

Aim: To compare & evaluate the caries excavation efficacy of BRIX3000, Carie Care & Smart burs.

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The field assessment technique to evaluate the plants with a fungal phytopathogen for their tolerance to the disease is one of the crucial steps in dissecting their genetic control and in developing the resistant crop varieties. The objective behind this study was to develop and evaluate a field-based non-injury method of inoculation technique for Sclerotinia stem rot (SSR) in oilseed Brassica, caused by Sclerotinia sclerotiorum (Lib.) de Bary.

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Aim And Objectives: The study aimed at assessment of microwave assisted tissue fixation, processing and staining and to determine if it can replace standard formalin fixed paraffin embedded processing in tissues of different thickness.

Materials And Methods: Specimens from buccal mucosa and gingiva was used in the study and were divided into three different thickness and was fixed, processed and stained according to conventional method and with a use of kitchen microwave oven respectively. The present study is the first of its kind where oral tissues was fixed, processed and stained with a kitchen microwave in three different thickness.

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Varicella zoster virus (VZV) results in chicken pox and herpes zoster. Female rats show a higher level of herpes zoster associated pain than males, consistent with human studies. In this study, we addressed the novel hypothesis that sex difference in herpes zoster associated pain is due, in part, to estradiol modulating activity in the thalamus.

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Herpes zoster or shingles is the result of varicella zoster virus (VZV) infection and often results in chronic pain that lasts for months after visible symptoms subside. Testosterone often attenuates pain in males. Previous work demonstrates ovarian estrogen effects γ-aminobutyric acid (GABA) signaling in the thalamus, reducing pain but the role of testosterone within the thalamus is currently unknown.

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White mold or stem rot disease are ubiquitously distributed throughout the world and the causal organism of this disease (Lib.) de Bary, is known to infect over 400 plant species. Sclerotinia stem rot is one of the most devastating fungal diseases and poses a serious threat to the worldwide cultivation of oilseed including India.

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The optic neuroepithelial continuum of vertebrate eye develops into three differentially growing compartments: the retina, the ciliary margin (CM), and the retinal pigment epithelium (RPE). Neurofibromin 2 (Nf2) is strongly expressed in slowly expanding RPE and CM compartments, and the loss of mouse Nf2 causes hyperplasia in these compartments, replicating the ocular abnormalities seen in human NF2 patients. The hyperplastic ocular phenotypes were largely suppressed by heterozygous deletion of Yap and Taz, key targets of the Nf2-Hippo signaling pathway.

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Pain is a common complication of herpes zoster (HZ) infection which results from reactivation of a latent varicella zoster virus (VZV). A third of HZ patients' progress to a chronic pain state known as post herpetic neuralgia (PHN), and about a quarter of these patients' have orofacial pain. The mechanisms controlling the pain responses are not understood.

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