Synopsis of recent research by authors named "Mahesh Radhakrishnan"
- Mahesh Radhakrishnan's recent research primarily focuses on exploring the pathophysiological links between mental health disorders, particularly depression and anxiety, with various biological and environmental factors, including obesity, traumatic brain injury, and diabetes.
- His studies emphasize the therapeutic potential of novel pharmacological compounds, particularly serotonin type 3 (5-HT3) receptor antagonists and phosphodiesterase-4 inhibitors, in treating depression-related disorders, demonstrating their efficacy in preclinical models and elucidating underlying biochemical mechanisms.
- Radhakrishnan also investigates shared neurobiological pathways between depression and neurodegenerative diseases such as Alzheimer's, underscoring the complexities of mood disorders and their potential overlap with neurological conditions, thereby directing future therapeutic strategies.
