Publications by authors named "Mahesh M"

Background: While many clinical computed tomography (CT) protocols use helical scanning, the traditional method for measuring the volume CT Dose Index (CTDI) requires modifying the helical protocol to perform a single axial rotation. This modification can present challenges and mismatched settings across various scanner models.

Purpose: This study investigates the generalizability of a helical methodology for estimating CTDI across a diverse range of participants, CT scanner models, and protocol parameters.

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Plant-growth-promoting (PGP) endophytic bacteria are beneficial microorganisms that can help plants withstand biotic stress caused by fungal phytopathogens. In the present study, 78 endophytic bacterial isolates were isolated from chilli (Capsicum annuum L.).

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Objective: This study sought to determine consensus opinions from subspecialty radiologists and imaging physicists on the relative importance of image quality features in CT.

Methods: A prospective survey of subspecialty radiologists and medical physicists was conducted to collect consensus opinions on the relative importance of ten image quality features: axial sharpness, blooming, contrast, longitudinal sharpness, low contrast axial sharpness, metal artifact, motion, noise magnitude, noise texture, and streaking. The survey was first sent to subspecialty radiologists in volunteer leadership roles in the American College of Radiology and Radiological Society of North America, thereafter relying on snowball sampling.

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  • Emamectin Benzoate (EB) is an insecticide effective against certain pests, but it can disrupt neurotransmitters in invertebrates, leading to paralysis.
  • Human poisoning cases are very rare, with only five documented incidents, two of which were fatal, emphasizing the need for better treatment information.
  • This report describes a case of an adult male who ingested EB, experienced severe symptoms, and was treated successfully without long-term effects after four days in the hospital.
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  • - The study investigates how microwave treatment affects the phytochemical content, antioxidant properties, and anti-nutritional factors of de-oiled rice bran, with results varying based on wattage and duration of treatment.
  • - Total phenolics and flavonoids showed mixed results depending on microwave settings, while flavonol content consistently increased; some antioxidant activities improved with microwaving, but overexposure at high power decreased these benefits.
  • - Metabolomics analysis revealed variations in specific metabolites after treatment, suggesting that tailored microwaving can enhance beneficial compounds in de-oiled rice bran without significantly affecting overall metabolite levels.
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  • * Cow waste, while often used as fertilizer or fuel, poses environmental risks if not disposed of properly; however, anaerobic digestion and composting can convert it into valuable resources like biofuels and organic fertilizers.
  • * The study uses bibliometric analysis to examine current trends in cow waste applications, including innovative methods for extracting cellulose, producing biochar, and generating bioenergy while also evaluating the environmental impacts and benefits of these technologies.
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Introduction: Acetabular fractures, resulting from high-energy trauma, present significant orthopaedic challenges. Despite their rarity, the incidence of these fractures is rising, necessitating a comprehensive understanding of their epidemiological characteristics, especially in diverse populations like India.

Methods: This retrospective study analyzed data from 3643 patients across four level-1 trauma centers in India (North 1, North 2, West, and South) from January 2001 to December 2019.

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Background Urolithiasis, characterized by the formation of stones in the urinary tract, is a common condition with significant morbidity. Medical expulsive therapy (MET) has emerged as a non-invasive treatment modality for facilitating the spontaneous passage of ureteral stones. However, MET success varies widely among individuals, and identifying predictive factors for treatment outcomes is crucial for optimizing patient care.

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Background: The ultimate goal of advanced procedures in prosthetic dentistry is to construct a prosthesis based on the accurate reproduction of condylar guidance.

Aim: To compare the sagittal condylar inclination obtained using the cone-beam computed tomography (CBCT), panoramic image, and two articulator systems.

Settings And Design: A cross-sectional study was carried out in 20 dentate patients in the age group of 20-40 years.

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  • Cenchrus americanus, a crucial millet crop primarily grown in arid regions, was observed in Mysore, India, experiencing spathe blight and leaf spot disease during July 2021, affecting 5-8% of the surveyed fields.
  • Diseased samples showed brown, spotty lesions, and the pathogen responsible was identified as Curvularia sp. through morphological characteristics and molecular methods.
  • Pathogen identification involved analyzing fungal colonies and comparing DNA sequences of the isolates to reference sequences, confirming 100% similarity with Curvularia spicifera.
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Introduction: Sexual dysfunction (SD) is a common and distressing symptom for people living with multiple sclerosis (MS). Populations included in existing studies of SD may not fully reflect the diversity of people living with MS, with important implications for wider applicability. We aimed to evaluate reporting of sex, gender identity, sexual orientation, and ethnicity across studies of SD in MS.

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Medical imaging is both valuable and essential in the care of patients. Much of this imaging depends on ionizing radiation with attendant responsibilities for judicious use when performing an examination. This responsibility applies in settings of both individual as well as multiple (recurrent) imaging with associated repeated radiation exposures.

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Rationale: As per International Council for Harmonization (ICH) drug stability test guideline Q1A(R2), inherent stability characteristics of a drug should be studied. This work was designed to investigate inherent degradation characteristics of the drug idelalisib under ICH prescribed stress conditions, identify its degradation products, and postulate their corresponding degradation pathways.

Methods: Idelalisib was subjected to the ICH prescribed conditions of hydrolytic (neutral, acidic, and alkaline), photolytic, oxidative, and thermal stress according to ICH guideline Q1A(R2).

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  • Chia is a commercially important crop in India, particularly in Karnataka, where a field survey revealed signs of virescence with symptoms affecting 2-4% of the crop in a 30-hectare area.
  • The symptoms included malformed shoots, thickened stems, and reduced floral parts characterized by greenish florets.
  • DNA analysis confirmed the presence of phytoplasma associated with the symptoms, specifically identifying it as Candidatus Phytoplasma aurantifolia with high sequence similarity to other known phytoplasmas.
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Background: US nuclear capable shipyard workers have increased potential for occupational radiation exposure.

Objective: The aim of the study is to examine solid tumor mortality risks at low doses.

Method: 437,937 workers working from 1957 to 2004 at eight US shipyards were studied.

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  • Standards for evaluating image quality in multi-detector CT (MDCT) and cone-beam CT (CBCT) are being updated to align with new technologies, necessitating effective quality assurance methods suitable for various systems.
  • The study aimed to test the feasibility of using a single test phantom for ongoing image quality assessments in both MDCT and CBCT, employing semiautomated analysis tools for efficient data collection.
  • Results indicated that semiautomated quantitative metrics revealed important insights for quality assurance, highlighting variations due to system performance and setup, and establishing control limits for QA actions.
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Because ionizing radiation is widely used in medical imaging and in military, industry, and commercial applications, programmatic management and advancement in knowledge is needed, especially related to the health effects of low-dose radiation. The U.S.

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Background: The population prevalence of multimorbidity (the existence of at least 2 or more long-term conditions [LTCs] in an individual) is increasing among young adults, particularly in minority ethnic groups and individuals living in socioeconomically deprived areas. In this study, we applied a data-driven approach to identify clusters of individuals who had an early onset multimorbidity in an ethnically and socioeconomically diverse population. We identified associations between clusters and a range of health outcomes.

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