Improved rank-based recursive feature elimination method based ovarian cancer detection model via customized deep architecture.

Background: Ovarian cancer is often considered the most lethal gynecological cancer because it tends to be diagnosed at an advanced stage, leading to limited treatment options and poorer outcomes. Several factors contribute to the challenges in managing ovarian cancer, namely rapid metastasis, genetic factors, reproductive history, etc. This necessitates the prompt and precise diagnosis of ovarian cancer in order to carry out efficient treatment plans and give patients who are all impacted by OC the care and support they need.

Geotechnical performance of black cotton clay in the presence of lead and cadmium solutions for geoenvironmental application.

The usage of bentonites and sand-bentonite mixtures as liners has become prevalent due to their low permeability. However, these materials are scarce and prohibitively expensive in India. Black cotton clay (BCC) was chosen as an alternative clay liner for this research due to its abundance in India and its mineralogical composition.

Ocular effects of eye cosmetic formulations.

Objective: To study the ocular effects seen among eye cosmetic wearers in the Indian Population.

Methods: This cross-sectional study was conducted on female participants who had fulfilled the inclusion and exclusion criteria. A detailed history was obtained and thorough ophthalmic evaluation was done.

3D genomic mapping reveals multifocality of human pancreatic precancers.

Pancreatic intraepithelial neoplasias (PanINs) are the most common precursors of pancreatic cancer, but their small size and inaccessibility in humans make them challenging to study. Critically, the number, dimensions and connectivity of human PanINs remain largely unknown, precluding important insights into early cancer development. Here, we provide a microanatomical survey of human PanINs by analysing 46 large samples of grossly normal human pancreas with a machine-learning pipeline for quantitative 3D histological reconstruction at single-cell resolution.

Digital Survey Assessment of Individual and Occupational Factors Associated with Musculoskeletal Disorders among Indian Ophthalmologists.

Purpose: To study the prevalence of musculoskeletal disorder (MSD) and the associated occupational risk factors among Indian ophthalmologists, including residents and fellows.

Methods: A cross-sectional survey was conducted among ophthalmologists in India using a semi-structured questionnaire in a web-based survey. The questionnaire was prepared in English after extensive literature research and consulting with subject experts.

A study on knowledge, attitude, and practices toward ophthalmic emergencies among fresh medical graduates in India.

Purpose: The purpose of this study was to evaluate and estimate the knowledge, attitude, and practices of Indian fresh medical graduates with respect to ophthalmic emergencies.

Materials And Methods: This cross-sectional study was conducted on 1300 participants who had completed compulsory rotatory residential internship with the help of a questionnaire distributed through social platforms. The Chi-square and Pearson's coefficient relation tests were used.

Characterization of Post-COVID-19 Clinical Manifestations Among Patients Visiting a Post-COVID-19 Clinic in a Tertiary Care Center: A Descriptive Study.

Background On December 21, 2019, a pneumonia-like outbreak of an unknown cause or origin was found to be emerging in Wuhan, China. In India, the first case of COVID-19 was found in Kerala and then started to spread all over India. Most of the infected people have recovered from the disease, but some patients were found to have symptoms at post-discharge follow-up.

Sighting Dominance, Biometric Parameters, and Refractive Status Analyzing the Role of Ocular Dominance.

Objectives: The purpose was to study the association between ocular dominance, refractive status, and biometric parameters.

Methods: Ocular dominance was assessed on consenting participants with non-pathological eyes using "hole-in-the-card test." The participants were then examined for visual acuity, biometric measurements, and refraction.

Study of retinal nerve fiber layer thickness in diabetic patients using optical coherence tomography.

Purpose: This study aimed to assess and compare the changes in peripapillary retinal nerve fiber layer (RNFL) thickness in nondiabetics and diabetics with various stages of diabetic retinopathy (DR).

Methods: The study subjects were divided into four groups based on their diabetic status and findings, namely, controls (normal subjects without diabetes [NDM]), diabetics without retinopathy (NDR), nonproliferative DR (NPDR), and proliferative DR (PDR). Peripapillary RNFL thickness was assessed using optical coherence tomography.

Quantitative Analysis of Tear Film in Patients on Atypical Antipsychotics.

Purpose: To evaluate and compare the prevalence and severity of dry eye disease (DED) among patients on atypical antipsychotics with controls.

Methods: This cross-sectional study was conducted on patients who were on atypical antipsychotic therapy (study group) and matched controls (control group). Prevalence of DED was assessed using tear break up time.

A study on the perception, knowledge, attitude, and practices of eye donation among fresh medical graduates in India.

Objective: The objective of the study was to assess the perception, knowledge, attitude, and practices of eye donation among fresh medical graduates in India.

Materials And Methods: Responses to a semi-structured questionnaire were collected from 410 respondents using an online Google Form which were analyzed using IBM SPSS software version 21.

Results: First information source about eye donation was textbooks (31%), while ophthalmologists accounted for 10.

Comparison of smartphone application-based visual acuity with traditional visual acuity chart for use in tele-ophthalmology.

Purpose: The aim of this study was to compare the visual acuity (VA) by smartphone-based applications - EyeChart and the Peek Acuity to the standard Snellen chart to explore the possibility of using them as an alternative in tele-ophthalmology in the current COVID-19 pandemic.

Materials And Methods: An analytical type of observational study was done on 360 eyes of 184 patients above 18 years of age. Patients with VA <6/60 and gross ocular pathology were excluded from the study.

Metabolic Syndrome in Post-Pulmonary Tuberculosis-Associated Obstructive Airway Disease: A Cross-Sectional Analytical Study.

Background The aim of this study is to assess the prevalence of metabolic syndrome in tuberculosis-associated obstructive airway disease (TOPD) patients, as well as the association of its components with the severity of airflow obstruction. Methodology In this cross-sectional analytical study, we evaluated the clinical profile, spirometry, waist circumference, blood pressure, lipid profile, fasting plasma glucose, and the association of each component with the severity of airflow obstruction. Results The prevalence of metabolic syndrome in TOPD was found to be was 25.

Evaluation of post-COVID health status using the EuroQol-5D-5L scale.

SARS-CoV-2 has had a lasting effect on the overall health of recovered patients, called 'long COVID'. Currently, there is a lack of a validated standard questionnaire to assess post-COVID health status. A retrospective observational study involving the recovered COVID patients admitted to a secondary care hospital in India between June to December 2020 (n = 123), was conducted using the EuroQol-5D-5L scale at discharge, 4 weeks and 8 weeks post-discharge.

Ipsilateral floating hip and knee, or floating lower limb - A rare case report.

Introduction: Ipsilateral floating hip and knee injuries at the same time are very rare injuries, occurring due to high velocity trauma. With a small number of such case reports, the treatment guidelines regarding surgical fixation are yet to be formulated.

Case Report: We report an interesting case of hip dislocation, comminuted acetabular fracture, intertrochanteric and shaft of femur fracture and both bones leg fracture ipsilaterally.

Pulmonary Manifestations in Systemic Sclerosis: Hospital-Based Descriptive Study.

Introduction Prevalence of systemic sclerosis (SSc)-related organ injury is difficult to estimate as it occurs early in SSc, even though patients are often asymptomatic. As the patients with organ damage have a poor prognosis, all the patients should be carefully evaluated and followed‑up in the initial periods. This facilitates the early identification and initiation of appropriate therapy.

Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study.

Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years).

Hearing Improvement After Type III Tympanoplasty: A Prospective Observational Study.

To analyse the postoperative hearing results of patients undergoing type III tympanoplasty using sculptured homologous spur cartilage. This prospective study included 156 patients of chronic otitis media (COM), between the ages 10-60 years. All cases underwent type III tympanoplasty with ossiculoplasty using homologous spur cartilage.

Expression of Human Papillomavirus DNA and p53 Polymorphisms through Polymerase Chain Reaction in Normal Mucosa and Oral Leukoplakia Individuals with Deleterious Oral Habits.

Context: Oral leukoplakia (OL) is a well-recognized precancerous lesion with various etiological factors. Most commonly deleterious oral habits such as tobacco smoking and viral etiologies mainly human papillomavirus (HPV) play an important role. p53 polymorphisms mostly homozygous Arginine (Arg) allele has a greater risk of degradation by HPV.

Dentigerous Cyst Associated with Adenomatoid Odontogenic Tumour.

Adenomatoid odontogenic tumour (AOT), a tumour composed of odontogenic epithelium, is an uncommon tumour of odontogenic origin that accounts for only 2.2- 7.1% of all odontogenic tumours.

Experimental studies on the effect of different metallic substrates on marine biofouling.

In the wake of adoption of the resolution by the International Maritime Organization to control biofouling on vessels, which is recognized as a major vector for transfer of invasive species, this study attempts to create a baseline data on major hard-shelled biofouling organisms in the harbour waters. This study was primarily focused towards understanding the biofouling and corrosion pattern on various metals and their performance under immersed condition in a marine environment, at 0.3 and 3.

A Ten Year Retrospective Study on Adult Tetanus at the Epidemic Disease (ED) Hospital, Mysore in Southern India: A Review of 512 Cases.

Background: Tetanus still remains a major public health problem in India like in most other developing countries, with a high morbidity and mortality.

Objectives: To study the socio-demographic profile and the clinical profile that they presented with, as well as the outcome of the tetanus patients who were admitted to the E.D Hospital, Mysore in India.

A comparative study on microwave and routine tissue processing.

Aim And Objective: The present study was aimed at assessing the rapid microwave-assisted tissue processing and staining to determine if it can replace standard formalin-fixed and paraffin-embedded processing and staining technique.

Materials And Methods: The study group consisted of 15 oral mucosal biopsies. The specimens were fixed in 10% formalin for 24 hours to ensure adequate fixation and their gross features were recorded, photographed, and then the specimens were cut into equal halves to be processed by both conventional and microwave histoprocessing methods and then subsequently stained with H and E by microwave and conventional methods.