Biologically active ionic chitosan Schiff base nanocomposites: Synthesis, characterization and antimicrobial activity against Helicobacter pylori.

1-(2-((4-Bromophenyl)amino)-2-oxoethyl)pyridin-1-ium chloride Schiff base (CH-Py) was prepared via reacting (CH) with pyridine-3-carboxaldehyde, followed by reacting the product with N-(4-bromophenyl)-2-chloroacetamide. The structure of the resulting CH derivative was determined viaHNMR and FTIR. The CH-Py derivative was converted into nanoparticles (CH-Py-Cl NPs) using sodium tripolyphosphate (TPP).

Synthesis of novel chitosan-Schiff bases nanoparticles for high efficiency Helicobacter pylori inhibition.

Two chitosan Schiff bases were synthesized by condensation of chitosan with 2-(4-formylphenoxy)-N-phenylacetamide and N-(4-bromophenyl)-2-(4-formylphenoxy) acetamide denoted as Cs-SBA and Cs-SBBr, respectively. The molecular structures of the resulting chitosan derivatives were characterized using FTIR and HNMR and their thermal properties were investigated by TGA. These derivatives were treated with sodium tripolyphosphate (TPP) to produce Cs Schiff base nanoparticles.

Synthesis and biological evaluation against H. pylori of chitosan menthone Schiff base hybrid with different types of inorganic nanoparticles.

The production of novel natural medicines for the treatment of Helicobacter pylori (H. pylori) has lately attracted a lot of interest. Some bacterial infections have traditionally been alleviated by terpenes.

Chitosan Schiff bases-based polyelectrolyte complexes with graphene quantum dots and their prospective biomedical applications.

Chitosan (Cs) bis-aldehyde Schiff base derivatives were synthesized by condensation of Cs with three bis-aldehydes namely; butane-1,4-diyl bis(4-formylbenzoate), N,N'-(butane-1,4-diyl)bis(2-(4-formylphenoxy)acetamide) and 4,4'-(butane-1,4-diylbis(oxy))dibenzaldehyde. The prepared Cs derivatives were blended with carboxymethyl chitosan(CMC) and graphene quantum dots (GQDs) to produce semi-IPNs polyelectrolyte complexes (PECs). and characterized with respect to their molecular structure and physio-chemical properties.

Chitosan-based delivery systems for plants: A brief overview of recent advances and future directions.

Chitosan has been termed as the most well-known among biopolymers, receiving widespread attention from researchers in various fields mainly, agriculture, food, and health. Chitosan is a deacetylated derivative of chitin, mainly isolated from waste shells of the phylum Arthropoda after their consumption as food. Chitosan molecules can be easily modified for adsorption and slow release of plant growth regulators, herbicides, pesticides, and fertilizers, etc.

Synthesis, characterization and antimicrobial activity of a novel chitosan Schiff bases based on heterocyclic moieties.

Three heteroaryl pyrazole derivatives; namely 1-phenyl-3-(thiophene-2-yl)-1H-pyrazole-4-carbaldehyde, 1-phenyl-3-(furan-2-yl)-1H-pyrazole-4-carbaldehyde and 1-phenyl-3-(pyridine-3-yl)-1H-pyrazole-4-carbaldehyde were synthesized and reacted with chitosan to form Schiff bases of chitosan. All newly synthesized compounds have been characterized by solubility tests, elemental analysis, spectral (FTIR, H NMR) analyses, thermogravimetric analysis and X-ray diffraction (XRD). The Schiff bases were screened for their biological activity against gram-negative bacteria (Escherichia coli and Klebsiella pneumonia), gram-positive bacteria (Staphylococcus aureus and Streptococcus mutans) and fungi (Asperagillus fumigatus and Candida albican).

Current advancements in chitosan-based film production for food technology; A review.

Chitosan is obtained from chitin, which could be considered to be the most abundant polymer after cellulose. Owing to these properties, chitosan alone or chitosan-based composite film production is attaining huge attention in terms of applications from researchers and industrialists coming from divergent fields. To enhance the biological (mainly antimicrobial and antioxidant) and physiological (mainly mechanical, thermal and barrier) attributes of the chitosan-based films, a vast medley of plant extracts and supporting polymers has been blended into chitosan films.

Synthesis and characterization of some acyl thiourea derivatives of chitosan and their biocidal activities.

Three acyl derivatives of chitosan (CS) with different side chains were synthesized and their structures were characterized. Their swelling behavior was investigated. The antifungal behavior of these chitosan derivatives was investigated in vitro on the mycelial growth, sporulation and germination of conidia or sclerotia of the sugar-beet pathogens, Rhizoctonia solani K"uhn (AG2-2) and Sclerotium rolfsii Sacc.

Chitosan based edible films and coatings: a review.

Chitosan is a biodegradable biocompatible polymer derived from natural renewable resources with numerous applications in various fields, and one of which is the area of edible films and coatings. Chitosan has antibacterial and antifungal properties which qualify it for food protection, however, its weak mechanical properties, gas and water vapor permeability limit its uses. This review discusses the application of chitosan and its blends with other natural polymers such as starch and other ingredients for example essential oils, and clay in the field of edible films for food protection.

Chitosan based nanofibers, review.

Chitin and chitosan are natural polymers with a huge potential in numerous fields, namely, biomedical, biological, and many industrial applications such as waste water treatment due to the fact that they can absorb and chelate many metal cations. Electrospinning is a growing field of research to produce submicron fibers with promising applications in biomedical fields like tissue engineering scaffolds and wound healing capabilities. Both chitin and chitosan polymers were found to be hard to electrospun, however, many researchers manage to produce nano-fibers using special solvents; for example, 90% acetic acid was found to reduce the surface tension making electrospinning feasible.

Surface active properties of chitosan and its derivatives.

This review discusses the definition of surface active agents and specifically natural polymeric surface active agents. Chitosan by itself was found to have weak surface activity since it has no hydrophobic segments. Chemical modifications of chitosan could improve such surface activity.

Extraction and characterization of chitin and chitosan from local sources.

Chitin has been extracted from six different local sources in Egypt. The obtained chitin was converted into the more useful soluble chitosan by steeping into solutions of NaOH of various concentrations and for extended periods of time, then the alkali chitin was heated in an autoclave which dramatically reduced the time of deacetylation. Chitin from squid pens did not require steeping in sodium hydroxide solution and showed much higher reactivity towards deacetylation in the autoclave that even after 15 min of heating a degree of deacetylation of 90% was achieved.